酿酒酵母ade3基因座的二分结构。
Bipartite structure of the ade3 locus of Saccharomyces cerevisiae.
作者信息
Jones E W
出版信息
Genetics. 1977 Feb;85(2):209-23. doi: 10.1093/genetics/85.2.209.
Abstract
Forty ade3 mutants were examined with respect to their growth requirements, levels of the tetrahydrofolate interconversion enzymes, and/or map positions. Four deletions were detected. Mutations that result in a requirement for adenine and histidine map in one region of the locus; those which result in a requirement for adenine only map in a quite separate region of the locus, a region not disclosed in previous studies. No correlation was observed between growth properties of the strains and enzyme levels.
摘要
对40个ade3突变体进行了生长需求、四氢叶酸转化酶水平和/或图谱位置的检测。检测到4个缺失。导致对腺嘌呤和组氨酸有需求的突变位于该位点的一个区域；而那些仅导致对腺嘌呤有需求的突变位于该位点一个完全不同的区域，这是之前研究中未揭示的区域。未观察到菌株的生长特性与酶水平之间存在相关性。
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