Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Bahia 45029-094, Brazil.
Departamento de Fisiologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, São Paulo 14049-900, Brazil.
Exp Biol Med (Maywood). 2020 Jul;245(13):1142-1154. doi: 10.1177/1535370220928986. Epub 2020 Jun 2.
Diabetic kidney disease (DKD) is associated with increased mortality in diabetic patients and has a negative impact on public health. The identification of potential therapies that help the management of DKD can contribute to the improvement of health and quality of life of patients. Thus, this paper is timely and relevant because, in addition to presenting a concise review of the pathogenesis and major pathophysiological mechanisms of DKD, it addresses the most recent findings on the impact of exercise training on this disease. Thus, since non-pharmacological interventions have gained increasing attention in the fight against chronic diseases, this paper appears as an important tool to increase knowledge and stimulate innovative research on the impact of exercise on kidney disease.
糖尿病肾病(DKD)与糖尿病患者的死亡率增加有关,对公共健康有负面影响。确定有助于 DKD 管理的潜在治疗方法可以有助于改善患者的健康和生活质量。因此,本文是及时和相关的,因为它除了简要回顾了 DKD 的发病机制和主要病理生理机制外,还涉及了关于运动训练对这种疾病影响的最新发现。因此,由于非药物干预在对抗慢性疾病方面越来越受到关注,本文作为一个重要的工具,可以增加关于运动对肾脏疾病影响的知识,并激发创新性研究。