Palatini P, Berton G, Mos L, Businaro R, Martina S, Racioppa A, Penzo M, Petek A M, Pessina A C, Dal Palù C
Clinica Medica I, Università di Padova.
G Ital Cardiol. 1988 Nov;18(11):926-33.
Short-term blood pressure variability has been studied extensively with monitoring techniques. To assess whether or not and to what extent average 24-hour blood pressure varies when repeatedly recorded, 12 mild to moderate hypertensive subjects underwent 3 non-invasive blood pressure monitorings at monthly intervals. When the average 24-hour blood pressure of the whole group was evaluated no substantial differences were found between the 3 recordings, even though slightly lower blood pressure values were recorded at the first monitoring. However, when the within-period comparison was studied in the single patients, remarkable discrepancies of up to 20.9/15.8 mmHg were detected. Systolic and diastolic blood pressure variations greater than or equal to 5 mmHg were recorded in 58% of the subjects. These differences were unrelated to the number of faulty readings. Casual blood pressure varied even to a greater extent between the first and the subsequent visits; no correlation was found between casual and 24-hour blood pressure variations. The results of the present study indicate that ambulatory blood pressure may vary even to a great extent when repeatedly recorded. This finding entails important clinical implications, as the evaluation of the hypertensive patient is usually made with a single blood pressure monitoring.
短期血压变异性已通过监测技术进行了广泛研究。为了评估反复记录时24小时平均血压是否以及在何种程度上会发生变化，12名轻度至中度高血压患者每隔一个月接受3次无创血压监测。在评估整个组的24小时平均血压时，尽管第一次监测记录的血压值略低，但在3次记录之间未发现实质性差异。然而，当在单个患者中研究期间内比较时，检测到高达20.9/15.8 mmHg的显著差异。58%的受试者收缩压和舒张压变化大于或等于5 mmHg。这些差异与错误读数的数量无关。在首次就诊和随后就诊之间，偶然血压的变化甚至更大；偶然血压与24小时血压变化之间未发现相关性。本研究结果表明，动态血压在反复记录时甚至可能有很大变化。这一发现具有重要的临床意义，因为高血压患者的评估通常是通过单次血压监测进行的。
