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直接前路与后外侧入路全髋关节置换术后血红蛋白及功能恢复的自然转归:一项随机研究。

Natural outcome of hemoglobin and functional recovery after the direct anterior versus the posterolateral approach for total hip arthroplasty: a randomized study.

机构信息

Department of Joint Surgery and Sports Medicine, Shanghai Changzheng Hospital, Second Military Medical University, No.415, Fengyang Road, Shanghai, 200003, China.

出版信息

J Orthop Surg Res. 2020 Jun 1;15(1):200. doi: 10.1186/s13018-020-01716-4.

Abstract

BACKGROUND

Total hip arthroplasty (THA) is one of the most successful orthopedic surgeries. There are many common surgical approaches for THA. The direct anterior approach (DAA) and posterolateral approach (PLA) were compared, leading to controversial results.

METHODS

We report on a prospective randomized study which compared the changes of perioperative hemoglobin (Hb), the Harris hip score (HHS) and a visual analog scale (VAS) pain score following THA using DAA or PLA. A total of 130 participants were randomly divided into two groups (65 DAA versus 65 PLA). Perioperative ΔHb and other clinical outcomes were recorded.

RESULTS

A total of 130 participants completed follow-up, while 14 patients were not recorded in blood outcomes due to blood transfusions and complications. The average Hb decrease immediately after surgery in the DAA group was greater than that in the PLA group (21.1 versus 15.8 g/L, P < .001). However, post-operative Hb descent velocity was slower in the DAA group, and the lowest point was reached earlier. No significant differences in ΔHb levels could be observed after 1 month in the two groups. When compared with the PLA group, the DAA group had a shorter incision (9.1 versus 13.5 cm, P < .001) and shorter hospital stay (4.2 versus 4.7 days, P = .004). However, the operation time of the DAA group was longer (88.0 versus 66.8 min, P < .001). The DAA group had a better HHS and VAS pain score at 6 weeks post-surgery. However, no significant differences were observed at later time points.

CONCLUSION

We concluded that DAA performed better on enhanced recovery after surgery (ERAS) than PLA in THA, while both DAA and PLA could result in a positive, similar result after 3 months.

TRIAL REGISTRATION

The study was registered by the Chinese Clinical Trial Registry (ChiCTR1900020770, 19 January 2019).

摘要

背景

全髋关节置换术(THA)是最成功的矫形外科手术之一。THA 有许多常见的手术入路。直接前侧入路(DAA)和后侧外侧入路(PLA)进行了比较,结果存在争议。

方法

我们报告了一项前瞻性随机研究,比较了 DAA 和 PLA 用于 THA 术后围手术期血红蛋白(Hb)变化、Harris 髋关节评分(HHS)和视觉模拟评分(VAS)疼痛评分。共有 130 名参与者被随机分为两组(65 名 DAA 与 65 名 PLA)。记录围手术期 ΔHb 和其他临床结果。

结果

共有 130 名参与者完成了随访,而由于输血和并发症,有 14 名患者未记录血液结果。DAA 组术后即刻 Hb 下降幅度大于 PLA 组(21.1 与 15.8 g/L,P <.001)。然而,DAA 组术后 Hb 下降速度较慢,最低点出现较早。两组术后 1 个月时,ΔHb 水平无显著差异。与 PLA 组相比,DAA 组的切口更小(9.1 与 13.5 cm,P <.001),住院时间更短(4.2 与 4.7 天,P =.004)。然而,DAA 组的手术时间更长(88.0 与 66.8 min,P <.001)。术后 6 周,DAA 组的 HHS 和 VAS 疼痛评分更好。然而,在稍后的时间点,没有观察到显著差异。

结论

我们的结论是,与 PLA 相比,DAA 在 THA 中更能提高术后快速康复(ERAS),而 DAA 和 PLA 在 3 个月后都能产生积极、相似的结果。

试验注册

该研究在中国临床试验注册中心注册(ChiCTR1900020770,2019 年 1 月 19 日)。

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