Department of Orthopedic Surgery, Kanazawa University School of Medicine, Kanazawa, Japan.
Department of Orthopedic Surgery, Philippine Orthopedic Center, Manilla, Philippines.
Anticancer Res. 2020 Jun;40(6):3551-3557. doi: 10.21873/anticanres.14344.
BACKGROUND/AIM: Previous studies have identified pelvic tumors as a risk factor for surgical site infections (SSI). However, risk factors for extremity tumors are still unclear. This study investigated risk factors for postoperative deep infection in malignant bone tumors of the extremities.
Data from 238 patients with 256 malignant bone tumor surgeries were reviewed. Univariate analysis and multiple logistic regression determined risk factors for deep infection.
Deep infection was found in 23 of 256 cases (9.0%). Tibial tumor (OR=6.04; 95%CI=2.14-17.05; p<0.001) and operative time ≥5 hours (OR=3.25; 95%CI=1.15-9.23; p=0.027) were independent risk factors for deep infection.
Tibial tumor and operative time ≥5 hours are independent risk factors for deep infection after surgery of malignant bone tumor of extremities. Strategies to minimize risk of infection in the tibia and decreasing operative time should be implemented, along with other measures to decrease SSI.
背景/目的：先前的研究已经确定盆腔肿瘤是手术部位感染（SSI）的一个危险因素。然而，肢体肿瘤的危险因素仍不清楚。本研究调查了四肢恶性骨肿瘤术后深部感染的危险因素。
回顾了 238 例 256 例恶性骨肿瘤手术患者的数据。单因素分析和多因素逻辑回归确定了深部感染的危险因素。
256 例中发现 23 例（9.0%）深部感染。胫骨肿瘤（OR=6.04；95%CI=2.14-17.05；p<0.001）和手术时间≥5 小时（OR=3.25；95%CI=1.15-9.23；p=0.027）是深部感染的独立危险因素。
胫骨肿瘤和手术时间≥5 小时是四肢恶性骨肿瘤手术后深部感染的独立危险因素。应采取策略最小化胫骨感染风险并缩短手术时间，同时采取其他措施降低 SSI。
