Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125.
Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125
Genetics. 2020 Jun;215(2):297-322. doi: 10.1534/genetics.120.303258.
Mesoderm migration in the embryo is a highly conserved, complex process that is required for the formation of specialized tissues and organs, including the somatic and visceral musculature. In this FlyBook chapter, we will compare and contrast the specification and migration of cells originating from the trunk and caudal mesoderm. Both cell types engage in collective migrations that enable cells to achieve new positions within developing embryos and form distinct tissues. To start, we will discuss specification and early morphogenetic movements of the presumptive mesoderm, then focus on the coordinate movements of the two subtypes trunk mesoderm and caudal visceral mesoderm, ending with a comparison of these processes including general insights gained through study.
原肠胚中的中胚层迁移是一个高度保守的复杂过程，对于形成专门的组织和器官，包括躯体和内脏肌肉，是必需的。在这个果蝇手册的章节中，我们将比较和对比源自中胚层的细胞的特化和迁移。这两种细胞类型都参与了集体迁移，使细胞能够在发育中的胚胎中获得新的位置，并形成不同的组织。首先，我们将讨论假定中胚层的特化和早期形态发生运动，然后集中讨论两种亚型中胚层和尾内脏中胚层的协调运动，最后比较这些过程，包括通过研究获得的一般见解。
