Continuum (Minneap Minn). 2020 Jun;26(3):577-590. doi: 10.1212/CON.0000000000000871.
This article describes the neurologic sequelae of various nutritional micronutrient deficiencies, celiac disease, inflammatory bowel disease, and liver disease. Where relevant, appropriate treatments for these conditions are also discussed. The developing field of the microbiome and nervous system interaction is also outlined.
Pathology in the gastrointestinal system can affect the nervous system when it causes micronutrient deficiency, when immune responses created by the gastrointestinal system affect the nervous system, when toxins caused by gastrointestinal organ failure harm the nervous system, and when treatments aimed at a gastrointestinal medical condition cause damage to the nervous system as a side effect.
This article addresses familiar concepts and new developments in the treatment and understanding of diseases that affect the gut and nervous system simultaneously.
本文描述了各种营养微量营养素缺乏、乳糜泻、炎症性肠病和肝病的神经后遗症。在相关情况下,还讨论了这些疾病的适当治疗方法。本文还概述了微生物组和神经系统相互作用的新兴领域。
当胃肠道疾病引起的微营养素缺乏、胃肠道系统产生的免疫反应影响神经系统、胃肠道器官衰竭引起的毒素损害神经系统以及针对胃肠道疾病状况的治疗作为副作用对神经系统造成损害时,胃肠道系统的病理学就会影响神经系统。
本文讨论了影响胃肠道和神经系统的疾病的治疗和理解方面的常见概念和新进展。