Sarangapani S, Giner J, Soeldner J S, Colton C K, Picha G, Mayhan K G, Drake R F
Giner Inc., Waltham, MA.
Horm Metab Res Suppl. 1988;20:43-7.
High surface area platinum subjected to the appropriate electrical potential cycling regimes exhibits considerable electrocatalytic activity towards glucose oxidation. We have developed a special data processing method, the compensated net charge (CNC) method, to take advantage of the electrocatalytic activity of platinum. This method involves the determination of the net oxidation charge during one complete cycle of a cyclic voltammogram applied to the platinum electrode in a potentiodynamic mode. Under these conditions, the electrode response is very sensitive to glucose, completely insensitive to urea, and only moderately sensitive to amino acid concentration changes. Earlier work with other endogenous and exogenous potential co-reactants shows little interference. Data obtained in vitro and in vivo will be presented and discussed.
具有高表面积的铂在适当的电势循环条件下对葡萄糖氧化表现出相当大的电催化活性。我们开发了一种特殊的数据处理方法——补偿净电荷（CNC）法，以利用铂的电催化活性。该方法涉及在恒电势模式下应用于铂电极的循环伏安图的一个完整周期内确定净氧化电荷。在这些条件下，电极响应对葡萄糖非常敏感，对尿素完全不敏感，对氨基酸浓度变化仅适度敏感。早期对其他内源性和外源性潜在共反应物的研究显示干扰很小。将展示并讨论在体外和体内获得的数据。
