McConnell I, Lachmann P J
Immunol Commun. 1977;6(2):111-32. doi: 10.3109/08820137709055806.
Membrane receptors for activated complement components are widely distributed amongst tissue cells of most mammalian species. Common amongst these are receptors for C3b which mediate many of the biological functions of C3. In addition, the genetic control of certain complement components is linked to the genes which code for the major histocompatibility complex. Many of these components are also present on cell surfaces. This suggests that the function of the complement system and the major histocompatibility complex may be related.
活化补体成分的膜受体广泛分布于大多数哺乳动物物种的组织细胞中。其中常见的是C3b受体,它介导C3的许多生物学功能。此外,某些补体成分的遗传控制与编码主要组织相容性复合体的基因相关联。这些成分中的许多也存在于细胞表面。这表明补体系统和主要组织相容性复合体的功能可能相关。