• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

颈部淋巴结结核的治疗:何时应进行手术?一项回顾性队列研究。

Treatment of cervical lymph node tuberculosis: When surgery should be performed? A retrospective cohort study.

作者信息

Lekhbal Adil, Chaker Kaoutar, Halily Sara, Abada Reda Lah, Rouadi Sami, Roubal Mohamed, Mahtar Mohamed

机构信息

ENT Department, Face and Neck Surgery, Hospital August, 20'1953, University Hospital Centre IBN ROCHD, Casablanca, Morocco.

出版信息

Ann Med Surg (Lond). 2020 May 18;55:159-163. doi: 10.1016/j.amsu.2020.05.006. eCollection 2020 Jul.

DOI:10.1016/j.amsu.2020.05.006
PMID:32489658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7256428/
Abstract

BACKGROUND

lymph node tuberculosis is the most common form of extra pulmonary tuberculosis. Although diagnosis is usually difficult, therapeutic management remains a challenge and a subject of national and international debate.

MATERIALS AND METHODS

the medical records of patients with cervical lymph node tuberculosis who were treated at 20 August Hospital, Casablanca, Morocco, between May 2017 and November 2018 were reviewed. The results of the treatment were analyzed retrospectively.The aim of our work was to identify all causes of medical treatment failure in cervical lymph node tuberculosis, and to propose indications for the use of surgery in cervical lymph node tuberculosis in Morocco.

RESULTS

Out of a total of 104 patients, the mean age was 24 years, the sex ratio was 0.51 (women: 66.3%), twenty (19.2%) patients received medical treatment alone, and 84 (80.8%) patients required medical and surgical treatment. Surgery was required when the size of the lymphadenopathies was greater than or equal to 3 cm (p = 0.005), when the patient presented with an abscess and/or fistula(p = 0.005), when the patient presented with resistance to antibacillary drugs(p = 0.032), or developed a paradoxical upgrading reactions (p = 0.001), or when the patient had a recurrence of lymph node tuberculosis(p = 0.008) on multivariate analysis.

CONCLUSION

antibiotic therapy remains the main treatment for all patients in lymph node tuberculosis, but the results of our work show the value of surgery in some indications.

摘要

背景

淋巴结结核是肺外结核最常见的形式。尽管诊断通常困难,但治疗管理仍然是一项挑战,也是国内和国际争论的主题。

材料与方法

回顾了2017年5月至2018年11月在摩洛哥卡萨布兰卡20日医院接受治疗的颈淋巴结结核患者的病历。对治疗结果进行回顾性分析。我们工作的目的是确定颈淋巴结结核治疗失败的所有原因,并提出摩洛哥颈淋巴结结核手术治疗的指征。

结果

在总共104例患者中,平均年龄为24岁,性别比为0.51(女性:66.3%),20例(19.2%)患者仅接受药物治疗,84例(80.8%)患者需要药物和手术治疗。多因素分析显示,当淋巴结肿大大小大于或等于3 cm(p = 0.005)、患者出现脓肿和/或瘘管(p = 0.005)、患者对抗结核药物耐药(p = 0.032)、出现矛盾性加剧反应(p = 0.001)或淋巴结结核复发(p = 0.008)时,需要进行手术。

结论

抗生素治疗仍然是所有淋巴结结核患者的主要治疗方法,但我们的工作结果显示了手术在某些指征下的价值。

相似文献

1
Treatment of cervical lymph node tuberculosis: When surgery should be performed? A retrospective cohort study.颈部淋巴结结核的治疗:何时应进行手术?一项回顾性队列研究。
Ann Med Surg (Lond). 2020 May 18;55:159-163. doi: 10.1016/j.amsu.2020.05.006. eCollection 2020 Jul.
2
The Role of Surgery in the Treatment of Cervical Lymph Node Tuberculosis.手术在颈部淋巴结结核治疗中的作用
Cureus. 2023 May 10;15(5):e38824. doi: 10.7759/cureus.38824. eCollection 2023 May.
3
Paradoxical reaction associated with cervical lymph node tuberculosis: predictive factors and therapeutic management.与颈淋巴结结核相关的矛盾反应:预测因素和治疗管理。
Int J Infect Dis. 2017 Jan;54:4-7. doi: 10.1016/j.ijid.2016.10.025. Epub 2016 Oct 31.
4
[Cervical tuberculous lymphadenitis: the location of surgery].
J Otolaryngol Head Neck Surg. 2009 Feb;38(1):23-8.
5
A clinical review of 38 cases of cervical tuberculous lymphadenitis in Japan - The role of neck dissection.日本38例颈部结核性淋巴结炎的临床回顾——颈淋巴结清扫术的作用
Auris Nasus Larynx. 2016 Dec;43(6):672-6. doi: 10.1016/j.anl.2016.01.002. Epub 2016 Feb 5.
6
Systemic lymph node tuberculosis presenting with an aseptic psoas abscess caused by a paradoxical reaction after nine months of antituberculosis treatment: a case report.抗结核治疗九个月后出现反常反应导致无菌性腰大肌脓肿的系统性淋巴结结核:一例报告
J Med Case Rep. 2013 Mar 14;7:72. doi: 10.1186/1752-1947-7-72.
7
Suppurative cervical lymphadenitis in adult: An analysis of predictors for surgical drainage.成人化脓性颈淋巴结炎:手术引流预测因素分析
Auris Nasus Larynx. 2020 Oct;47(5):887-894. doi: 10.1016/j.anl.2020.04.007. Epub 2020 May 1.
8
Late paradoxical lymph node enlargement during and after anti-tuberculosis treatment in non-HIV-infected patients.非HIV感染患者抗结核治疗期间及治疗后出现的迟发性矛盾性淋巴结肿大。
Int J Tuberc Lung Dis. 2015 Nov;19(11):1388-94. doi: 10.5588/ijtld.15.0257.
9
[Long-term oncological outcomes after laparoscopic versus abdominal radical hysterectomy in stage I a2- II a2 cervical cancer: a matched cohort study].[I a2-II a2期宫颈癌腹腔镜与开腹根治性子宫切除术后的长期肿瘤学结局:一项配对队列研究]
Zhonghua Fu Chan Ke Za Zhi. 2015 Dec;50(12):894-901.
10
[Cervical lymph node tuberculosis: diagnosis and treatment].
Ann Otolaryngol Chir Cervicofac. 2009 Nov-Dec;126(5-6):250-5. doi: 10.1016/j.aorl.2009.09.001.

引用本文的文献

1
Analysis of bleeding after ultrasound-guided core needle biopsy of infected cervical lymph nodes.超声引导下感染性颈部淋巴结粗针穿刺活检后出血情况分析
Front Surg. 2025 Aug 8;12:1589238. doi: 10.3389/fsurg.2025.1589238. eCollection 2025.
2
Extrapulmonary Comparisons Between and Non-Tuberculous Mycobacteria: From Manifestations and Diagnosis to Treatment.肺外非结核分枝杆菌之间的比较:从临床表现、诊断到治疗
Infect Drug Resist. 2025 May 22;18:2613-2627. doi: 10.2147/IDR.S515196. eCollection 2025.
3
Value of contrast-enhanced ultrasound assisted core needle biopsy in the diagnosis of cervical lymph node tuberculosis.超声造影辅助粗针穿刺活检在颈部淋巴结结核诊断中的价值
Front Oncol. 2025 Apr 17;15:1570133. doi: 10.3389/fonc.2025.1570133. eCollection 2025.
4
Extrapulmonary tuberculosis in Morocco: A systematic review of observational studies.摩洛哥的肺外结核病:观察性研究的系统评价
Rev Soc Bras Med Trop. 2025 Mar 17;58:e004022024. doi: 10.1590/0037-8682-0066-2024. eCollection 2025.
5
Relationship among ultrasound features, pus Mycobacterium tuberculosis load, and efficacy of antituberculosis drugs in patients with necrotizing tuberculous lymphadenitis.坏死性结核性淋巴结炎患者超声特征、脓液结核分枝杆菌载量与抗结核药物疗效的关系。
Sci Rep. 2024 Dec 6;14(1):30413. doi: 10.1038/s41598-024-82444-1.
6
The value of histopathologic examination and Xpert (MTB/RIF) assay in diagnosis of cervical lymph node tuberculosis after coarse needle biopsy guided by CEUS: a retrospective analysis of 612 cases.超声造影引导下粗针穿刺活检后组织病理学检查及Xpert(MTB/RIF)检测在颈部淋巴结结核诊断中的价值:612例回顾性分析
Eur J Clin Microbiol Infect Dis. 2024 Oct;43(10):1951-1957. doi: 10.1007/s10096-024-04913-9. Epub 2024 Aug 1.
7
Can Ultrasound Evaluation of Lymph Node Size and Necrosis Rate Predict Chemotherapy Response in Cervical Tuberculous Lymphadenitis?超声评估淋巴结大小及坏死率能否预测颈淋巴结结核化疗反应?
Infect Drug Resist. 2024 Jul 16;17:3073-3079. doi: 10.2147/IDR.S467827. eCollection 2024.
8
Lymph node dissection effectively shortens the course of anti-tuberculosis treatment.淋巴结清扫术有效缩短了抗结核治疗疗程。
J Clin Tuberc Other Mycobact Dis. 2023 Sep 25;33:100399. doi: 10.1016/j.jctube.2023.100399. eCollection 2023 Dec.
9
The value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs.多模态超声在评估颈淋巴结结核对抗结核药物治疗反应中的价值
Front Med (Lausanne). 2023 Jul 18;10:1177045. doi: 10.3389/fmed.2023.1177045. eCollection 2023.
10
Value of Contrast-Enhanced Ultrasound in the Ultrasound Classification of Cervical Tuberculous Lymphadenitis.超声造影在颈部结核性淋巴结炎超声分类中的价值
Front Med (Lausanne). 2022 Jun 14;9:898688. doi: 10.3389/fmed.2022.898688. eCollection 2022.

本文引用的文献

1
Evaluation of the Yield of Histopathology in the Diagnosis of Lymph Node Tuberculosis in Morocco, 2017: Cross-Sectional Study.2017年摩洛哥淋巴结结核组织病理学诊断阳性率评估:横断面研究
JMIR Public Health Surveill. 2019 Oct 9;5(4):e14252. doi: 10.2196/14252.
2
The STROCSS statement: Strengthening the Reporting of Cohort Studies in Surgery.STROCSS 声明:加强外科学队列研究报告。
Int J Surg. 2017 Oct;46:198-202. doi: 10.1016/j.ijsu.2017.08.586. Epub 2017 Sep 7.
3
A clinical review of 38 cases of cervical tuberculous lymphadenitis in Japan - The role of neck dissection.日本38例颈部结核性淋巴结炎的临床回顾——颈淋巴结清扫术的作用
Auris Nasus Larynx. 2016 Dec;43(6):672-6. doi: 10.1016/j.anl.2016.01.002. Epub 2016 Feb 5.
4
TUBERCULOUS CERVICAL LYMPHADENOPATHY AND THE ROLE OF SURGICAL TREATMENT.结核性颈淋巴结病与外科治疗的作用
Southeast Asian J Trop Med Public Health. 2014 Nov;45(6):1419-24.
5
Current diagnosis and management of peripheral tuberculous lymphadenitis.外周结核性淋巴结炎的当前诊断和治疗。
Clin Infect Dis. 2011 Sep;53(6):555-62. doi: 10.1093/cid/cir454.
6
Post-therapy paradoxical response in immunocompetent patients with lymph node tuberculosis.免疫功能正常的淋巴结结核患者治疗后出现矛盾反应。
J Infect. 2010 Nov;61(5):430-4. doi: 10.1016/j.jinf.2010.08.011. Epub 2010 Sep 8.
7
Tuberculous lymphadenitis.结核性淋巴结炎
J Assoc Physicians India. 2009 Aug;57:585-90.
8
Paradoxical responses in non-HIV-infected patients with peripheral lymph node tuberculosis.非HIV感染的外周淋巴结结核患者的矛盾反应。
J Infect. 2009 Jul;59(1):56-61. doi: 10.1016/j.jinf.2009.05.006. Epub 2009 May 28.
9
Peripheral tuberculous lymphadenitis: epidemiology, diagnosis, treatment, and outcome.外周结核性淋巴结炎:流行病学、诊断、治疗及转归
Medicine (Baltimore). 2005 Nov;84(6):350-362. doi: 10.1097/01.md.0000189090.52626.7a.
10
Treatment of lymph node tuberculosis--a randomized clinical trial of two 6-month regimens.淋巴结结核的治疗——两种6个月治疗方案的随机临床试验
Trop Med Int Health. 2005 Nov;10(11):1090-8. doi: 10.1111/j.1365-3156.2005.01493.x.