Belloni Fortina Anna, Caroppo Francesca, Tadiotto Cicogna Giulia
Pediatric Dermatology Unit, Department of Medicine DIMED, University of Padova , Padova, Italy.
Expert Rev Clin Immunol. 2020 Jun;16(6):579-589. doi: 10.1080/1744666X.2020.1777858. Epub 2020 Jun 15.
Allergic contact dermatitis is an inflammatory skin disease which accounts for up to 20% of all childhood dermatitis. Childhood allergic contact dermatitis is more frequent than previously thought and today early diagnosis is considered very important. Patch testing represents the gold standard method used to confirm the diagnosis of allergic contact dermatitis. The knowledge of the most common allergens involved in allergic contact dermatitis in pediatric age is important considering that the first-line management of allergic contact dermatitis in children is to avoid the involved allergens.
We reviewed the literature on PubMed® and SciVerse Scopus® medical database about allergic contact dermatitis and emerging contact allergens in children. In this review, we summarize the clinical characteristics, differential diagnoses, and epidemiology of allergic contact dermatitis in children, underlying the most recent pieces of evidence about the most frequent and emerging contact allergens.
We believe that persistent, well localized and recurrent eczematous lesions in children should suggest an allergic contact dermatitis, inducing physicians to refer patients for patch testing. Physicians should be acquainted with the current trends and the emerging contact allergens in children, in order to provide not only the best treatment but also the best management and prevention.
过敏性接触性皮炎是一种炎症性皮肤病,占所有儿童皮炎的20%。儿童过敏性接触性皮炎比以前认为的更为常见,如今早期诊断被认为非常重要。斑贴试验是用于确诊过敏性接触性皮炎的金标准方法。鉴于儿童过敏性接触性皮炎的一线治疗是避免接触相关过敏原,了解儿童过敏性接触性皮炎中最常见的过敏原非常重要。
我们检索了PubMed®和SciVerse Scopus®医学数据库中有关儿童过敏性接触性皮炎和新出现的接触性过敏原的文献。在本综述中,我们总结了儿童过敏性接触性皮炎的临床特征、鉴别诊断和流行病学,强调了有关最常见和新出现的接触性过敏原的最新证据。
我们认为,儿童持续存在、定位明确且反复发作的湿疹性皮损应提示过敏性接触性皮炎,促使医生将患者转诊进行斑贴试验。医生应了解儿童当前的趋势和新出现的接触性过敏原,以便不仅提供最佳治疗,还能提供最佳管理和预防措施。