Kuklik Helen Helene, Cruz Izabela Taiatella Siqueira Alves, Celli Adriane, Fraiz Fabian Calixto, AssunÇÃo Luciana Reichert da Silva
Universidade Federal do Paraná, Curitiba, PR, Brasil.
Arq Gastroenterol. 2020 Apr-Jun;57(2):167-171. doi: 10.1590/s0004-2803.202000000-31.
Molar incisor hypomineralization (MIH) is a developmental enamel defect with multifactorial etiology. Although the relationship between celiac disease (CD) and developmental enamel defect was demonstrated, the association between CD and MIH is uncertain.
The objective of this study was to analyze the occurrence of MIH in CD patients.
Forty CD patients and a control group with 40 healthy individuals were selected. A calibrated examiner (k≥0.889) according to the European Academy of Pediatric Dentistry criteria performed the diagnosis of MIH. Data were analyzed by descriptive statistics and Fischer's exact test (α=0.05).
Of the 80 participants, ten presented MIH with eight individuals with CD. Celiac patients presented 4.75 times the chance of occurrence of MIH than the control group (95% CI: 2.22-10.18; P=0.044). In all the evaluated teeth (n=978), 22 had MIH: 20 teeth in individuals with CD and two in those without the disease. All CD participants with MIH presented the classic form of the disease. CD participants showed 17 teeth (85.0%) with demarcated opacities, two (10.0%) post-eruptive collapses and one (5.0%) atypical restoration. The control group presented only demarcated opacities.
CD increased the chance of MIH and associated with its clinical manifestations can assist in the diagnosis of CD.
磨牙切牙矿化不全(MIH)是一种病因多因素的牙釉质发育缺陷。尽管乳糜泻(CD)与牙釉质发育缺陷之间的关系已得到证实,但CD与MIH之间的关联尚不确定。
本研究的目的是分析CD患者中MIH的发生率。
选取40例CD患者和40名健康个体作为对照组。一名经过校准的检查者(k≥0.889)根据欧洲儿童牙科学会标准对MIH进行诊断。采用描述性统计和Fisher精确检验(α=0.05)对数据进行分析。
80名参与者中,有10人患有MIH,其中8人患有CD。CD患者发生MIH的几率是对照组的4.75倍(95%CI:2.22-10.18;P=0.044)。在所有评估的牙齿(n=978)中,有22颗患有MIH:CD患者中有20颗牙齿,无该疾病的患者中有2颗牙齿。所有患有MIH的CD参与者均表现出该疾病的典型形式。CD参与者中有17颗牙齿(85.0%)出现界限清晰的混浊,2颗(10.0%)出现萌出后牙体折裂,1颗(5.0%)出现非典型修复。对照组仅出现界限清晰的混浊。
CD增加了MIH的发生几率,且与MIH的临床表现相关,这有助于CD的诊断。