新型冠状病毒2型感染患者的神经并发症：一项系统综述
Neurological complications in patients with SARS-CoV-2 infection: a systematic review.
作者信息
Munhoz Renato Puppi, Pedroso José Luiz, Nascimento Fábio Augusto, Almeida Sergio Monteiro de, Barsottini Orlando Graziani Povoas, Cardoso Francisco Eduardo C, Teive Hélio A Ghizoni
机构信息
Movement Disorders Centre, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada.
Department of Neurology and Neurosurgery, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
出版信息
Arq Neuropsiquiatr. 2020 May;78(5):290-300. doi: 10.1590/0004-282x20200051. Epub 2020 Jun 1.
BACKGROUND
As the COVID-19 pandemic unfolds worldwide, different forms of reports have described its neurologic manifestations.
OBJECTIVE
To review the literature on neurological complications of SARS-CoV-2 infection.
METHODS
Literature search performed following systematic reviews guidelines, using specific keywords based on the COVID-19 neurological complications described up to May 10th, 2020.
RESULTS
A total of 43 articles were selected, including data ranging from common, non-specific symptoms, such as hyposmia and myalgia, to more complex and life-threatening conditions, such as cerebrovascular diseases, encephalopathies, and Guillain-Barré syndrome.
CONCLUSION
Recognition of neurological manifestations of SARS-CoV-2 should be emphasized despite the obvious challenges faced by clinicians caring for critical patients who are often sedated and presenting other concurrent systemic complications.
背景
随着新冠疫情在全球范围内蔓延，各种形式的报告描述了其神经学表现。
目的
综述关于严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染神经并发症的文献。
方法
按照系统评价指南进行文献检索，使用基于截至2020年5月10日所描述的新冠神经并发症的特定关键词。
结果
共筛选出43篇文章，包括从常见的非特异性症状，如嗅觉减退和肌痛，到更复杂且危及生命的情况，如脑血管疾病、脑病和吉兰-巴雷综合征等数据。
结论
尽管照顾危重症患者的临床医生面临诸多明显挑战，这些患者常处于镇静状态且伴有其他并发的全身并发症，但仍应强调对SARS-CoV-2神经学表现的认识。
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