宫颈癌治疗中发病率降低及生存率提高。
Decreased morbidity and increased survival in cervical cancer treatment.
作者信息
Kumar P P, Good R R, Scott J C, Jones E O
出版信息
J Natl Med Assoc. 1988 Oct;80(10):1113-7.
Thirty-seven patients with previously untreated invasive carcinoma of the uterine cervix, International Federation of Gynecology and Obstetrics (FIGO) stages IB to IVA, were treated with 4,000 rad external beam radiotherapy (EXRT) to midplane, followed by two intracavitary endocurietherapy (ECT) applications of 2,500 rad each to point "A" using a Kumar applicator, for a total dose of 9,000 rad. The major complication rate was 2.7 percent, and the local control rate was 85 percent (22/26 patients) for stages IB and II, and 91 percent (10/11 patients) for stages III and IVA. The three-year uncorrected observed actuarial survival was 80.3 percent for stages IB and II, and 81.8 percent for stages III and IVA. The three-year adjusted actuarial survival rate was 95.2 percent for stages IB and II, and 90.5 percent for stages III and IVA.
37例既往未经治疗的子宫颈浸润癌患者，国际妇产科联盟（FIGO）分期为IB至IVA期，接受了4000拉德的盆腔中部外照射放疗（EXRT），随后使用Kumar施源器对“A”点进行两次腔内近距离放疗（ECT），每次剂量为2500拉德，总剂量为9000拉德。主要并发症发生率为2.7%，IB期和II期患者的局部控制率为85%（22/26例患者），III期和IVA期患者的局部控制率为91%（10/11例患者）。IB期和II期患者三年未校正的实际观察生存率为80.3%，III期和IVA期患者为81.8%。IB期和II期患者三年校正后的实际生存率为95.2%，III期和IVA期患者为90.5%。
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