Suppr超能文献

[新型冠状病毒2(严重急性呼吸综合征冠状病毒2,SARS-CoV-2)大流行对急性阑尾炎的影响]

[Influence of the coronavirus 2 (SARS-Cov-2) pandemic on acute appendicitis].

作者信息

Velayos María, Muñoz-Serrano Antonio Jesús, Estefanía-Fernández Karla, Sarmiento Caldas Ma Carmen, Moratilla Lapeña Lucas, López-Santamaría Manuel, López-Gutiérrez Juan Carlos

机构信息

Servicio de Cirugía Pediátrica. Hospital Universitario La Paz, Madrid, España.

Servicio de Cirugía Pediátrica. Hospital Universitario La Paz, Madrid, España.

出版信息

An Pediatr (Engl Ed). 2020 Aug;93(2):118-122. doi: 10.1016/j.anpedi.2020.04.022. Epub 2020 May 11.

Abstract

INTRODUCTION

Acute appendicitis (AA) is the most common abdominal surgical emergency. No specific studies have been found that evaluate the impact of the coronavirus 2 (SARS-Cov-2) pandemic on AA and its surgical management. An analysis was made on the influence of this new pathology on the clinical course of AA.

MATERIAL AND METHODS

Retrospective observational study was conducted on patients operated on for AA from January to April 2020. They were classified according to the time of the appendectomy, before the declaration of the state of alarm (pre-COVID-19), and after its declaration (post-COVID-19) in Spain, one the most affected countries in the world. An evaluation was made of demographic variables, duration of symptoms, type of appendicitis, surgical time, hospital stay, and postoperative complications.

RESULTS

The study included 66 patients (41 pre-COVID-19; 25 post-COVID-19) with mean age of 10.7 ± 3 and 9.3 ± 3.1; P = .073, respectively. Fever was found in a higher number of post-COVID-19 patients (52 vs. 19.5%; P = 0.013), as well as a higher CRP (72.7 ± 96.2 vs. 31.3 ± 36.2 mg/dL; P = 0.042). This group presented with a higher proportion of complicated appendicitis when compared to pre-COVID-19 (32 vs. 7.3%; P = 0.015). The mean hospital stay was longer in the post-COVID-19 group (5.6 ± 5.9 vs. 3.2 ± 4.3 days; P = 0.041). No differences were found in the time of onset of symptoms or surgical time.

CONCLUSIONS

The SARS-Cov-2 pandemic influenced the time of diagnosis of appendicitis, as well as its course, and mean hospital stay. Peritonitis was more frequently seen. As a result of the significant circumstances, delaying diagnosis and treatment of AA during SARS-Cov-2 pandemic, inappropriate management of this common surgical disorder has been noticed.

摘要

引言

急性阑尾炎(AA)是最常见的腹部外科急症。尚未发现有专门研究评估2019冠状病毒病(SARS-CoV-2)大流行对急性阑尾炎及其外科治疗的影响。本研究分析了这种新发病理对急性阑尾炎临床病程的影响。

材料与方法

对2020年1月至4月因急性阑尾炎接受手术的患者进行回顾性观察研究。根据阑尾切除术时间,将患者分为西班牙宣布进入警戒状态之前(COVID-19之前)和之后(COVID-19之后),西班牙是世界上受影响最严重的国家之一。评估了人口统计学变量、症状持续时间、阑尾炎类型、手术时间、住院时间和术后并发症。

结果

该研究纳入了66例患者(COVID-19之前41例;COVID-19之后25例),平均年龄分别为10.7±3岁和9.3±3.1岁;P=0.073。COVID-19之后的患者发热人数更多(52%对19.5%;P=0.013),C反应蛋白(CRP)也更高(72.7±96.2对31.3±36.2mg/dL;P=0.042)。与COVID-19之前相比,该组复杂阑尾炎的比例更高(32%对7.3%;P=0.015)。COVID-19之后组的平均住院时间更长(5.6±5.9天对3.2±4.3天;P=0.041)。症状出现时间或手术时间没有差异。

结论

SARS-CoV-2大流行影响了阑尾炎的诊断时间、病程及平均住院时间。腹膜炎更为常见。由于这些重大情况,在SARS-CoV-2大流行期间急性阑尾炎的诊断和治疗被延迟,已注意到对这种常见外科疾病的处理不当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/025f/7211733/c712def0edd8/gr1_lrg.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验