Postgraduate Program in Dentistry, Federal University of Sergipe, Aracaju, Brazil; Investigative Pathology Laboratory, Federal University of Sergipe, Sergipe, Brazil.
Investigative Pathology Laboratory, Federal University of Sergipe, Sergipe, Brazil.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul;130(1):71-77. doi: 10.1016/j.oooo.2020.02.019. Epub 2020 May 31.
The aim of this study was to investigate oral and maxillofacial outcomes in children with congenital Zika syndrome (CZS) and the presence of nonnutritive sucking habits, functional habits, and features related to breastfeeding and nutrition of these children.
We conducted a cross-sectional study with 45 children with CZS and 50 healthy controls in Sergipe state, Brazil, from February 2018 to June 2018. Demographic and clinical data, including breastfeeding and feeding data, were obtained for each child. Additionally, oral and maxillofacial evaluation was performed.
Low weight (prevalence rate [PR] 8.33; 95% confidence interval [CI] 2.02-34.45), nonexclusive breastfeeding up to 6 months (PR 1.56; 95% CI 1.18-2.08); mouth breathing (PR 3.46; 95% CI 1.83-6.52); difficulty in swallowing (PR 6.00; 95% CI 2.53-14.25); and excessive salivation (PR 4.81; 95% CI 2.18-10.62) were more frequent in children with CZS. Children with CZS were more likely to have abnormal insertion of the upper labial frenulum (PR 7.04; 95% CI 2.23-22.20); ogival palate (PR 3.70; 95% CI 1.63-8.40), dental enamel defects (PR 2.22; 95% CI 1.05-4.69); and delayed dental eruption (PR 8.89; 95% CI 1.16-68.32) compared with healthy children.
Children with CZS had a higher frequency of problems related to breastfeeding, low weight, and oral and maxillofacial abnormalities compared with healthy children.
本研究旨在调查先天性寨卡综合征（CZS）患儿的口腔颌面部结局，以及这些患儿非营养性吸吮习惯、功能习惯以及与母乳喂养和营养相关的特征的存在情况。
我们在巴西塞尔希培州进行了一项横断面研究，共纳入 45 例 CZS 患儿和 50 例健康对照儿童。我们获取了每个儿童的人口统计学和临床数据，包括母乳喂养和喂养数据。此外，我们还对口腔颌面部进行了评估。
低体重（发生率 [PR]8.33%；95%置信区间 [CI]2.02-34.45%）、6 个月前非纯母乳喂养（PR1.56%；95%CI1.18-2.08%）、口呼吸（PR3.46%；95%CI1.83-6.52%）、吞咽困难（PR6.00%；95%CI2.53-14.25%）和过度流涎（PR4.81%；95%CI2.18-10.62%）在 CZS 患儿中更为常见。CZS 患儿的上唇系带异常附着（PR7.04%；95%CI2.23-22.20%）、腭弓（PR3.70%；95%CI1.63-8.40%）、牙釉质发育不全（PR2.22%；95%CI1.05-4.69%）和牙齿萌出延迟（PR8.89%；95%CI1.16-68.32%）的可能性高于健康儿童。
与健康儿童相比，CZS 患儿在母乳喂养、低体重和口腔颌面部异常方面的问题更为常见。
