Deepika Keerti, Adhikari Ramesh, Adapa Sreedhar, Naramala Srikanth, Konala Venu Madhav
Pediatrics/Translational Research, Thomas Jefferson University, Philadelphia, USA.
Hospital Medicine, Franciscan Health Hospital, Lafayette, USA.
Cureus. 2020 Apr 30;12(4):e7898. doi: 10.7759/cureus.7898.
Eosinophilic esophagitis (EoE) is a clinicopathological condition characterized clinically by symptoms of esophageal dysfunction, with typical endoscopic findings and intra-epithelial eosinophilia on biopsy. This case report focuses on the historical aspect of EoE, clinical manifestations, and correlation with immune disorders, medical management, and interventional management of EoE. We present a 20-year-old patient presenting with tightness in throat and odynophagia after the ingestion of certain foods. These symptoms resolve in two or three hours. Endoscopic examination of the upper gastrointestinal tract visualizes esophageal stenosis, and histological examination of the biopsy specimen reveals increased eosinophils in the esophageal mucosa. The patient was treated with fluticasone inhaler and has shown improvement in symptoms. EoE is a chronic esophageal disorder that is increasing in incidence and prevalence in both pediatric and adult age groups. This case report accentuates the complications of EoE, and delays in diagnosis lead to strictures, and fibro-stenotic disease and punctual recognition can govern the course of the disease.
嗜酸性粒细胞性食管炎（EoE）是一种临床病理状态，临床上以食管功能障碍症状为特征，内镜检查有典型表现，活检显示上皮内嗜酸性粒细胞增多。本病例报告重点关注EoE的历史方面、临床表现、与免疫紊乱的相关性、医学管理以及EoE的介入管理。我们报告一名20岁患者，在摄入某些食物后出现喉咙发紧和吞咽疼痛。这些症状在两三个小时内缓解。上消化道内镜检查显示食管狭窄，活检标本的组织学检查显示食管黏膜中嗜酸性粒细胞增多。该患者接受氟替卡松吸入器治疗后症状有所改善。EoE是一种慢性食管疾病，在儿童和成人年龄组中的发病率和患病率都在增加。本病例报告强调了EoE的并发症，诊断延迟会导致狭窄、纤维狭窄性疾病，及时识别可控制疾病进程。
