在低耐甲氧西林环境下对检测出杀白细胞素的葡萄球菌菌血症患儿的临床表现：一项全国性调查
Clinical Manifestations in Children with Staphylococcal Bacteremia Positive for Panton-Valentine Leucocidin: A Nationwide Survey in a Low Methicillin-Resistance Setting.
作者信息
Bybeck Nielsen Allan, Larsen Anders Rhod, Petersen Andreas, Schønheyder Henrik Carl, Westh Henrik, Benfield Thomas, Nygaard Ulrikka
机构信息
From the Department of Pediatrics and Adolescent Medicine.
Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
出版信息
Pediatr Infect Dis J. 2020 Sep;39(9):e274-e276. doi: 10.1097/INF.0000000000002722.
A total of 714 pediatric cases of Staphylococcus aureus bacteremia were identified from 2008 to 2015 in Denmark; 98% were methicillin-susceptible S. aureus (MSSA). Fifteen isolates (2,1%) were Panton-Valentine leucocidin positive (0.17/100,000 children/year) and 87% MSSA. Eight cases (53%) were severe, including all pneumonia cases. Panton-Valentine leucocidin positive Staphylococcus aureus bacteremia is rare in our setting with high MSSA-prevalence. Half of the cases were uncomplicated.
2008年至2015年期间，丹麦共确诊714例儿童金黄色葡萄球菌菌血症病例；其中98%为甲氧西林敏感金黄色葡萄球菌（MSSA）。15株分离株（2.1%）为杀白细胞素阳性（每年每10万名儿童中有0.17例），且87%为MSSA。8例（53%）病情严重，包括所有肺炎病例。在我们所处的MSSA高流行环境中，杀白细胞素阳性金黄色葡萄球菌菌血症较为罕见。半数病例病情不复杂。
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