Hayakawa Yasunari, Inada Takayuki
Urawa Central Eye Institution, Saitama 336-0042, Japan.
Kawagoe Central Eye Institution, Kawagoe 350-1122, Japan.
J Clin Med. 2024 Sep 11;13(18):5378. doi: 10.3390/jcm13185378.
: To investigate whether it is better to perform minimally invasive glaucoma surgery (MIGS) when performing cataract surgery on glaucoma patients. : The study enrolled a total of 159 eyes of subjects with mild-to-moderate glaucoma, including primary open angle glaucoma (POAG), normal tension glaucoma (NTG), and combined mechanism glaucoma (CMG) with visually significant cataract, who were treated with one or more ophthalmic antiglaucoma agents. Phacoemulsification and aspiration with intraocular lens insertion (PEA + IOL, phaco group) or MIGS with PEA + IOL (µLot-phaco group) was performed on patients with glaucoma. Age, sex, glaucoma type, pre- and postoperative IOP, and ratio of IOP reduction were estimated. : The rate of IOP reduction in the µLot-phaco group was found to be significantly higher than in the phaco group at the 6-month postoperative assessment. Specifically, a strong correlation was observed between preoperative IOP levels, the presence of POAG, and patient age within the µLot-phaco group, all of which contributed significantly to the IOP reduction observed at the 6-month follow-up. : Simultaneous cataract and MIGS were found to be more effective in older POAG patients with higher preoperative IOP.
: 探讨青光眼患者在进行白内障手术时同期施行微创青光眼手术(MIGS)是否更好。: 该研究共纳入159只患有轻至中度青光眼的眼睛,包括原发性开角型青光眼(POAG)、正常眼压性青光眼(NTG)以及伴有具有临床意义白内障的混合型青光眼(CMG),这些患者均接受过一种或多种眼科抗青光眼药物治疗。对青光眼患者施行白内障超声乳化吸除联合人工晶状体植入术(PEA + IOL,白内障超声乳化组)或MIGS联合PEA + IOL(µLot-白内障超声乳化组)。评估患者的年龄、性别、青光眼类型、术前和术后眼压以及眼压降低率。: 在术后6个月评估时发现,µLot-白内障超声乳化组的眼压降低率显著高于白内障超声乳化组。具体而言,在µLot-白内障超声乳化组中,术前眼压水平、POAG的存在以及患者年龄之间存在强烈相关性,所有这些因素均对6个月随访时观察到的眼压降低有显著贡献。: 对于术前眼压较高的老年POAG患者,同期进行白内障手术和MIGS更为有效。