Department of Neuorsurgery, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.
Department of Otorhinolaryngology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.
World Neurosurg. 2020 Aug;140:166-172. doi: 10.1016/j.wneu.2020.05.236. Epub 2020 Jun 1.
Cerebrospinal fluid (CSF) leakage after penetrating skull base injury is relatively rare compared with close head injuries involving skull base fractures.
We report the case of a 65-year-old man who had presented with epistaxis and serous rhinorrhea. When he had fallen to the ground near his bee boxes, a garden pole had poked into his right nostril. He had instantly removed the pole from his nostril himself. However, immediately after removal of the pole, he had developed nasal bleeding and serous rhinorrhea. He then drove to our emergency room. Computed tomography showed pneumocephalus with a minor cerebral contusion in the left frontal lobe and a penetrating injury in the left anterior skull base. His CSF leakage had not resolve spontaneously within 1 week after the injury with strict bed rest. We repaired the CSF leakage using a fat (adipose tissue)-on-fascia autograft plug and caulked the defect in the anterior skull base with the fat-on-fascia graft (FFG) plug through the left nostril with endoscopic guidance. The CSF rhinorrhea was successfully controlled. Intranasal local application of fluorescein aided in the detection of the direction of flow of the CSF leakage.
Endonasal endoscopic caulking of a skull base defect using an FFG plug can be useful to treat CSF leakage due to the localized skull base defect, especially in the coronavirus disease 2019 pandemic. It is simple, inexpensive, and timesaving. It requires no special skills nor sophisticated instruments that can cause aerosolization, reducing the risk of infection during the surgery.
与涉及颅底骨折的近头部损伤相比,穿透性颅底损伤后发生脑脊液(CSF)漏相对较少。
我们报告了一例 65 岁男性患者,他出现鼻出血和浆液性鼻漏。当他在蜜蜂箱附近摔倒时,一根花园杆戳入他的右鼻孔。他立即自行将杆子从鼻孔中拔出。然而,杆子拔出后,他立即出现鼻出血和浆液性鼻漏。随后他被送到我们的急诊室。计算机断层扫描显示气颅,左额叶有轻微脑挫伤和穿透性颅前底损伤。他的 CSF 漏在受伤后 1 周内未自发缓解,严格卧床休息。我们使用脂肪(脂肪组织)-筋膜自体移植物塞修复 CSF 漏,并通过内窥镜引导从左鼻孔用脂肪-筋膜移植物(FFG)塞填塞颅前底的缺陷。CSF 鼻漏得到成功控制。鼻内局部应用荧光素有助于检测 CSF 漏的流向。
使用 FFG 塞经鼻内镜填塞颅底缺陷可有效治疗因局部颅底缺陷引起的 CSF 漏,尤其是在 2019 年冠状病毒病大流行期间。该方法简单、廉价、省时。它不需要特殊技能或可能引起气溶胶化的复杂仪器,从而降低手术过程中的感染风险。