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通过转入重症监护病房并给予右美托咪定治疗帕金森病患者的急性谵妄

Treatment of Acute Delirium in a Patient with Parkinson's Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine.

作者信息

Lombardo Morgan, DiPiazza Amanda, Rippey Kelly, Lubarr Naomi, Clar Elana, Azmi Hooman

机构信息

Department of Neurosurgery, Hackensack University Medical Center, Hackensack, NJ, USA.

North Jersey Brain and Spine Center, Hackensack, NJ, USA.

出版信息

J Mov Disord. 2020 May;13(2):159-162. doi: 10.14802/jmd.20005. Epub 2020 May 29.

DOI:10.14802/jmd.20005
PMID:32498499
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7280942/
Abstract

The treatment of delirium or psychosis in patients with Parkinson's disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute delirium is even more complicated in the hospital setting, as many medications deemed safer in this population are only available in oral form. We present a case of acute delirium in a patient with PD, likely precipitated by a polypharmacy interaction of new medications, that was successfully managed by transferring the patient to the intensive care unit and administering dexmedetomidine for 72 hours.

摘要

帕金森病（PD）患者谵妄或精神病的治疗可能会因该人群可用的药物种类有限而变得复杂。典型和非典型抗精神病药物是禁忌的，因为它们会加重运动症状。在医院环境中，急性谵妄的治疗更为复杂，因为许多被认为对该人群更安全的药物仅以口服形式提供。我们报告一例PD患者的急性谵妄病例，可能是由新药的多药相互作用引发的，通过将患者转入重症监护病房并给予右美托咪定72小时成功处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0634/7280942/a07e3f276173/jmd-20005f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0634/7280942/a07e3f276173/jmd-20005f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0634/7280942/a07e3f276173/jmd-20005f1.jpg

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Management of delirium in Parkinson's disease.帕金森病伴发谵妄的管理。
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