Department of neurology and stroke center, Versailles Mignot Hospital, 78150, Le Chesnay, France.
Department of angiology, Versailles Mignot Hospital, 78150, Le Chesnay, France.
BMC Neurol. 2020 Jun 4;20(1):229. doi: 10.1186/s12883-020-01797-y.
Arterial thoracic outlet syndrome is a rare condition characterized by a subclavian artery pathology associated with a bone abnormality. It is rarely associated with thromboembolic stroke. The mechanism of cerebral embolism associated with thoracic outlet syndrome have rarely been demonstrated. We present here a fully studied case with a high probability of reverse flow embolism.
A 24-year-old man with a known arterial thoracic outlet syndrome presented with a right cerebral posterior artery brain infarction. An ultrasound examination depicted the compression of the right subclavian artery in the scalene defile with a post stenotic aneurysm and the presence of a floating thrombus in this aneurysm. There was a reverse flow during diastole in this aneurysm. Anticoagulation was carried out with the disappearance of the floating thrombus with no new clinical or brain MRI event. Corrective surgery of this thoracic outlet syndrome was performed one month after stroke.
Very few cases of stroke in arterial thoracic outlet syndrome have been described with thorough dynamic vascular imaging. To our knowledge, this is the fourth reported case that advocates for a reverse flow embolism mechanism in stroke associated with thoracic outlet syndrome, and the first to realize an extensive ultrasound and doppler workup.
胸廓出口综合征是一种罕见的疾病,其特征是锁骨下动脉病变伴有骨异常。它很少与血栓栓塞性中风有关。与胸廓出口综合征相关的脑栓塞的机制很少被证明。我们在这里提出一个经过充分研究的病例,其反向血流栓塞的可能性很高。
一名 24 岁男性,已知患有动脉胸廓出口综合征,出现右侧大脑后动脉脑梗死。超声检查显示斜角肌间隙中右锁骨下动脉受压,狭窄后出现动脉瘤,该动脉瘤内有漂浮血栓。该动脉瘤在舒张期有反向血流。进行抗凝治疗后,漂浮血栓消失,无新的临床或脑 MRI 事件。中风后一个月对该胸廓出口综合征进行了矫正手术。
在有充分动态血管成像的情况下,很少有动脉胸廓出口综合征引起的中风病例被描述。据我们所知,这是第四个报告支持胸廓出口综合征相关中风中反向血流栓塞机制的病例,也是第一个进行广泛超声和多普勒检查的病例。