Department of Neurology, Saitama Medical University, 38 Morohongo Moroyama, Iruma-gun, Saitama, 350-0495, Japan.
BMC Neurol. 2020 Jun 4;20(1):228. doi: 10.1186/s12883-020-01815-z.
Recent studies have examined hypertrophic pachymeningitis as an IgG4-RD. However, there are no reports of immunoglobulin G4 (IgG4)-related hypertrophic pachymeningitis with polycystic subdural hygroma.
A 56-year-old man presented to the hospital with complaints of a persistent, pulsatile, occipital headache and general malaise. Magnetic resonance imaging of the brain revealed hypertrophic pachymeningitis with polycystic subdural hygroma and hematoma. Based on the dural biopsy findings and exclusion of other diseases, the patient was diagnosed with immunoglobulin G4 (IgG4)-related hypertrophic pachymeningitis. IgG4-related diseases may cause subdural hygroma more commonly than other diseases that cause hypertrophic pachymeningitis.
This is the first case report discussing polycystic subdural hygroma and hematoma with IgG4-related hypertrophic pachymeningitis.
最近的研究已经将肥厚性脑脊膜炎视为 IgG4-RD。然而，目前尚无 IgG4（免疫球蛋白 G4）相关肥厚性脑脊膜炎伴多囊性硬脑膜下腔积水的报道。
一名 56 岁男性因持续性、搏动性枕部头痛和全身不适就诊。脑部磁共振成像显示肥厚性脑脊膜炎伴多囊性硬脑膜下腔积水和血肿。根据硬脑膜活检结果并排除其他疾病，患者被诊断为 IgG4 相关肥厚性脑脊膜炎。与其他导致肥厚性脑脊膜炎的疾病相比，IgG4 相关疾病可能更常导致硬脑膜下腔积水。
这是首例讨论 IgG4 相关肥厚性脑脊膜炎伴多囊性硬脑膜下腔积水和血肿的病例报告。
