全身正电子发射断层扫描/计算机断层扫描在儿科成像中的潜在作用。
Potential Roles of Total-Body PET/Computed Tomography in Pediatric Imaging.
机构信息
Department of Radiology, University of California, Davis, ACC building Suite 3100, Sacramento, California 95817, USA.
Department of Radiology, University of California, Davis, ACC building Suite 3100, Sacramento, California 95817, USA; United Imaging Healthcare of America, Houston, TX, USA.
出版信息
PET Clin. 2020 Jul;15(3):271-279. doi: 10.1016/j.cpet.2020.03.009.
Abstract
In the current diagnostic paradigm, the substantial physical sensitivity gain is the main advantage of total-body (TB) PET/computed tomography (CT). Therefore, it is up to the imaging community to tailor protocols that take advantage of this unique innovation as it relates to the needs of the pediatric population. However, the paradigm-shifting promise of TB-PET/CT lies in its capability to perform dynamic, delayed, and low-dose imaging, which have the potential to vastly increase the range of diseases and disorders that can be investigated or managed using molecular imaging.
摘要
在当前的诊断模式中，全身（TB）PET/计算机断层扫描（CT）的显著物理灵敏度增益是其主要优势。因此，如何制定充分利用这一独特创新的协议取决于成像界，这与儿科人群的需求有关。然而，TB-PET/CT 带来的范式转变的承诺在于其进行动态、延迟和低剂量成像的能力，这有可能极大地增加可以使用分子成像进行研究或管理的疾病和病症的范围。
相似文献
1
Potential Roles of Total-Body PET/Computed Tomography in Pediatric Imaging.全身正电子发射断层扫描/计算机断层扫描在儿科成像中的潜在作用。
PET Clin. 2020 Jul;15(3):271-279. doi: 10.1016/j.cpet.2020.03.009.
2
Total-Body PET/Computed Tomography Highlights in Clinical Practice: Experiences from Zhongshan Hospital, Fudan University.全身正电子发射断层扫描/计算机断层扫描在临床实践中的应用亮点：来自复旦大学中山医院的经验。
PET Clin. 2021 Jan;16(1):9-14. doi: 10.1016/j.cpet.2020.09.007.
3
Oncologic Applications of Long Axial Field-of-View PET/Computed Tomography.轴向视野长的正电子发射断层扫描/计算机断层扫描在肿瘤学中的应用。
PET Clin. 2021 Jan;16(1):65-73. doi: 10.1016/j.cpet.2020.09.010.
4
18F-FDG PET/CT and whole-body MRI diagnostic performance in M staging for non-small cell lung cancer: a systematic review and meta-analysis.18F-FDG PET/CT 和全身 MRI 在非小细胞肺癌 M 分期中的诊断性能：系统评价和荟萃分析。
Eur Radiol. 2020 Jul;30(7):3641-3649. doi: 10.1007/s00330-020-06703-1. Epub 2020 Mar 3.
5
Clinical evaluation of CT radiation dose in whole-body F-FDG PET/CT in relation to scout imaging direction and arm position.全身¹⁸F-FDG PET/CT中CT辐射剂量与定位像扫描方向及手臂位置关系的临床评估
Ann Nucl Med. 2019 Mar;33(3):169-176. doi: 10.1007/s12149-018-1318-0. Epub 2018 Nov 10.
6
EFFECTIVE RADIATION DOSE OF 18F-FDG PET/CT: HOW MUCH DOES DIAGNOSTIC CT CONTRIBUTE?18F-FDG PET/CT的有效辐射剂量：诊断性CT的贡献有多大？
Radiat Prot Dosimetry. 2019 Dec 31;187(2):183-190. doi: 10.1093/rpd/ncz153.
7
Weight-based, low-dose pediatric whole-body PET/CT protocols.基于体重的低剂量儿科全身PET/CT协议。
J Nucl Med. 2009 Oct;50(10):1570-7. doi: 10.2967/jnumed.109.065912.
8
Diagnostic performance of F-FDG PET/CT and whole-body diffusion-weighted imaging with background body suppression (DWIBS) in detection of lymph node and bone metastases from pediatric neuroblastoma.18F-氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描（F-FDG PET/CT）及背景体部抑制全身扩散加权成像（DWIBS）在检测小儿神经母细胞瘤淋巴结及骨转移中的诊断效能
Ann Nucl Med. 2018 Jun;32(5):348-362. doi: 10.1007/s12149-018-1254-z. Epub 2018 Apr 17.
9
An Australian local diagnostic reference level for paediatric whole-body F-FDG PET/CT.澳大利亚儿童全身氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描（F-FDG PET/CT）的本地诊断参考水平
Br J Radiol. 2019 Apr;92(1096):20180879. doi: 10.1259/bjr.20180879. Epub 2019 Mar 5.
10
Assessment of Total-Body Atherosclerosis by PET/Computed Tomography.正电子发射断层扫描/计算机断层扫描评估全身动脉粥样硬化。
PET Clin. 2021 Jan;16(1):119-128. doi: 10.1016/j.cpet.2020.09.013. Epub 2020 Nov 5.
引用本文的文献
1
Total-Body Parametric Imaging Using Relative Patlak Plot.使用相对Patlak图的全身参数成像
J Nucl Med. 2025 Apr 1;66(4):654-661. doi: 10.2967/jnumed.124.268496.
2
Optimisation of low and ultra-low dose scanning protocols for ultra-extended field of view PET in a real-world clinical setting.在实际临床环境中对超宽视野PET的低剂量和超低剂量扫描协议进行优化。
Cancer Imaging. 2025 Jan 30;25(1):7. doi: 10.1186/s40644-025-00823-x.
3
Performance Characteristics of a New Generation 148-cm Axial Field-of-View uMI Panorama GS PET/CT System with Extended NEMA NU 2-2018 and EARL Standards.新一代148厘米轴向视野uMI全景GS PET/CT系统符合扩展的NEMA NU 2-2018和EARL标准的性能特征
J Nucl Med. 2024 Dec 3;65(12):1974-1982. doi: 10.2967/jnumed.124.267963.
4
QUALIPAED-A retrospective quality control study evaluating pediatric long axial field-of-view low-dose FDG-PET/CT.QUALIPAED——一项评估儿童长轴视野低剂量氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG-PET/CT）的回顾性质量控制研究。
Front Nucl Med. 2024 Jun 13;4:1398773. doi: 10.3389/fnume.2024.1398773. eCollection 2024.
5
Exploring the nigrostriatal and digestive interplays in Parkinson's disease using dynamic total-body [C]CFT PET/CT.使用动态全身 [C]CFT PET/CT 探索帕金森病中的黑质纹状体和消化系统相互作用。
Eur J Nucl Med Mol Imaging. 2024 Jul;51(8):2271-2282. doi: 10.1007/s00259-024-06638-5. Epub 2024 Feb 23.
6
Evolving roles of PET/CT and PET/MRI in assessing pediatric disorders with acceptable safety standards.PET/CT和PET/MRI在以可接受的安全标准评估儿科疾病中的作用演变。
Eur Radiol. 2024 May;34(5):3249-3251. doi: 10.1007/s00330-023-10385-w. Epub 2023 Nov 2.
7
A third of the radiotracer dose: two decades of progress in pediatric [F]fluorodeoxyglucose PET/CT and PET/MR imaging.放射性示踪剂剂量减少三分之一：儿科 [F]氟代脱氧葡萄糖 PET/CT 和 PET/MR 成像二十年的进展。
Eur Radiol. 2024 May;34(5):3252-3259. doi: 10.1007/s00330-023-10319-6. Epub 2023 Oct 19.
8
Pilot study on C-CFT dynamic imaging using total-body PET/CT: biodistribution and radiation dosimetry in Parkinson's disease.使用全身PET/CT进行C-CFT动态成像的帕金森病初步研究：生物分布与辐射剂量学
Front Neurol. 2023 May 16;14:1153779. doi: 10.3389/fneur.2023.1153779. eCollection 2023.
9
Comparison of the different imaging modalities used to image pediatric oncology patients: A COG diagnostic imaging committee/SPR oncology committee white paper.比较用于成像儿科肿瘤患者的不同成像方式：COG 诊断成像委员会/SRP 肿瘤委员会白皮书。
Pediatr Blood Cancer. 2023 Jun;70 Suppl 4(Suppl 4):e30298. doi: 10.1002/pbc.30298. Epub 2023 Apr 6.
10
Image quality assessment along the one metre axial field-of-view of the total-body Biograph Vision Quadra PET/CT system for F-FDG.针对F-FDG，在全身Biograph Vision Quadra PET/CT系统的1米轴向视野范围内进行图像质量评估。
EJNMMI Phys. 2022 Dec 14;9(1):87. doi: 10.1186/s40658-022-00516-5.
本文引用的文献
1
Subsecond total-body imaging using ultrasensitive positron emission tomography.使用超灵敏正电子发射断层扫描进行亚秒级全身成像。
Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2265-2267. doi: 10.1073/pnas.1917379117. Epub 2020 Jan 21.
2
Comparison of methods of quantifying global synovial metabolic activity with FDG-PET/CT in rheumatoid arthritis.类风湿关节炎中使用氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG-PET/CT）定量评估整体滑膜代谢活性的方法比较
Int J Rheum Dis. 2019 Dec;22(12):2191-2198. doi: 10.1111/1756-185X.13730. Epub 2019 Nov 13.
3
PennPET Explorer: Human Imaging on a Whole-Body Imager.PennPET Explorer：全身成像仪上的人体成像。
J Nucl Med. 2020 Jan;61(1):144-151. doi: 10.2967/jnumed.119.231845. Epub 2019 Sep 27.
4
Total-Body PET and Highly Stable Chelators Together Enable Meaningful Zr-Antibody PET Studies up to 30 Days After Injection.全身 PET 和高稳定性螯合剂的联合应用使 Zr 抗体的 PET 研究在注射后 30 天内具有有意义的结果。
J Nucl Med. 2020 Mar;61(3):453-460. doi: 10.2967/jnumed.119.230961. Epub 2019 Sep 27.
5
The Evolving Role of PET-Based Novel Quantitative Techniques in the Interventional Radiology Procedures of the Liver.基于正电子发射断层扫描（PET）的新型定量技术在肝脏介入放射学程序中的角色演变
PET Clin. 2019 Oct;14(4):419-425. doi: 10.1016/j.cpet.2019.06.004. Epub 2019 Aug 6.
6
Lutathera: The First FDA- and EMA-Approved Radiopharmaceutical for Peptide Receptor Radionuclide Therapy.镥[177Lu]奥曲肽：首个获美国食品药品监督管理局和欧洲药品管理局批准用于肽受体放射性核素治疗的放射性药物。
Pharmaceuticals (Basel). 2019 Jul 29;12(3):114. doi: 10.3390/ph12030114.
7
18F-FDG Is a Superior Indicator of Cognitive Performance Compared to 18F-Florbetapir in Alzheimer's Disease and Mild Cognitive Impairment Evaluation: A Global Quantitative Analysis.18F-FDG 在阿尔茨海默病和轻度认知障碍评估中比 18F-氟比他滨更能准确反映认知表现：一项全球定量分析。
J Alzheimers Dis. 2019;70(4):1197-1207. doi: 10.3233/JAD-190220.
8
Global disease score (GDS) is the name of the game!全球疾病评分（GDS）才是关键所在！
Eur J Nucl Med Mol Imaging. 2019 Aug;46(9):1768-1772. doi: 10.1007/s00259-019-04383-8. Epub 2019 Jun 10.
9
Evolving Role of PET-Based Novel Quantitative Techniques in the Management of Hematological Malignancies.基于正电子发射断层扫描（PET）的新型定量技术在血液系统恶性肿瘤管理中的不断演变的作用
PET Clin. 2019 Jul;14(3):331-340. doi: 10.1016/j.cpet.2019.03.003. Epub 2019 Apr 10.
10
The Potential Role of Total Body PET Imaging in Assessment of Atherosclerosis.全身PET成像在动脉粥样硬化评估中的潜在作用
PET Clin. 2019 Apr;14(2):245-250. doi: 10.1016/j.cpet.2018.12.007.
Zotero 插件