一种用于同时研究兔奥迪括约肌和十二指肠压力及电活动的模型。

A model for simultaneous study of pressure and electric events in the rabbit sphincter of Oddi and duodenum.

作者信息

Elbrønd H, Ostergaard L, Huniche B, Djurhuus J C

机构信息

Institute of Experimental Clinical Research, Arhus Kommunehospital, Denmark.

出版信息

Scand J Gastroenterol. 1988 Dec;23(10):1211-6. doi: 10.3109/00365528809090193.

DOI:10.3109/00365528809090193

PMID:3249919

Abstract

An animal experimental model featuring simultaneous recordings of electromyography and pressure from the sphincter of Oddi (SO) and duodenum is demonstrated. On the basis of data from 10 rabbits, pressure recordings from the SO were shown to have phasic activity with an average basic pressure peak interval of 2.6 to 3.5 sec. Histographic analysis of SO pressure recordings showed a multimodal appearance, suggesting that the activity is paced. A substantial amount of overlap between SO and duodenal contractions was observed. As many as 30% of the pressure peaks recorded from the SO could not be assigned to a spike complex in the corresponding EMG tracings. It is suggested that combined recordings of EMG and pressure activity are needed to characterize fully the motility of the SO and duodenum.

摘要

展示了一种同时记录肌电图以及来自Oddi括约肌（SO）和十二指肠压力的动物实验模型。基于10只兔子的数据，SO的压力记录显示出具有阶段性活动，平均基础压力峰值间隔为2.6至3.5秒。SO压力记录的直方图分析显示出多峰外观，表明该活动是有节律的。观察到SO和十二指肠收缩之间存在大量重叠。从SO记录的压力峰值中，多达30%无法在相应的肌电图描记中归属于一个尖峰复合体。建议需要同时记录肌电图和压力活动，以全面表征SO和十二指肠的运动。