Department of Production and Control of Medicines, School of Pharmacy, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Graduate Program in Epidemiology, School of Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
PLoS One. 2019 Mar 21;14(3):e0214329. doi: 10.1371/journal.pone.0214329. eCollection 2019.
To estimate the prevalence of use of analgesics in Brazil; and to characterize this use, according to sociodemographic and health-related characteristics.
A cross-sectional population-based study (National Survey on Access, Use and Promotion of Rational Use of Medicines, PNAUM) was conducted between September 2013 and February 2014. A total of 41,433 people of all ages in Brazilian urban households were interviewed. Occasional use (within the last 15 days) and continuous use of non-opioid analgesics, opioid analgesics and non-steroidal anti-inflammatory drugs were investigated, regardless of whether this use occurred through prescription or self-medication. The main outcome was the use of at least one analgesic.
The majority of the individuals were female (52.8%), aged between 20 and 59 years (57.2%), with 1 to 8 years of schooling (45.6%). The overall prevalence of analgesic use was 22.8% [95% CI: 21.4-24.2]. The use of analgesics was significantly higher among women, adults and elderly (20 years or more), highly educated individuals and respondents who referred: diagnosis of one or more chronic diseases, using three or more medications, possession of health insurance and with one or more emergency care admittances or hospitalizations within the last year. Non-opioid analgesics were the agents most used (18.5% of the sample), followed by non-steroidal anti-inflammatory drugs (6.9%) and opioid analgesics (0.5%). The most commonly used drugs were metamizole (37.8% of all analgesics), paracetamol (25.3%) and diclofenac (10.7%). These drugs were used mainly to manage occasional health conditions, particularly pain.
One in five Brazilians used some analgesic, especially non-opioid analgesics, to manage acute health problems such as painful conditions.
评估巴西使用镇痛药的流行情况;并根据社会人口学和与健康相关的特征对这种使用情况进行描述。
这是一项横断面的基于人群的研究(国家准入、使用和促进合理使用药物调查,PNAUM),于 2013 年 9 月至 2014 年 2 月进行。对巴西城市家庭中的所有年龄段的 41433 人进行了访谈。调查了非阿片类镇痛药、阿片类镇痛药和非甾体抗炎药的偶发性使用(在过去 15 天内)和连续使用情况,无论这种使用是通过处方还是自我用药。主要结果是使用至少一种镇痛药。
大多数参与者为女性(52.8%),年龄在 20 至 59 岁之间(57.2%),接受过 1 至 8 年的学校教育(45.6%)。镇痛药总体使用率为 22.8%(95%CI:21.4-24.2)。女性、成年人和老年人(20 岁及以上)、高学历者以及报告以下情况的人使用镇痛药的比例明显更高:诊断出一种或多种慢性疾病、使用三种或更多种药物、拥有健康保险以及在过去一年中因急症接受过一次或多次就诊或住院治疗。非阿片类镇痛药(样本的 18.5%)是最常使用的药物,其次是非甾体抗炎药(6.9%)和阿片类镇痛药(0.5%)。最常使用的药物是扑热息痛(所有镇痛药的 37.8%)、对乙酰氨基酚(25.3%)和双氯芬酸(10.7%)。这些药物主要用于治疗偶发性健康问题,尤其是疼痛。
五分之一的巴西人使用某种镇痛药,尤其是非阿片类镇痛药,来治疗急性健康问题,如疼痛状况。