Koduru Mallikarjuna Rao, Ail Sandeep, Shetty Jayarama, Shetty Vijith
Department of Radiotherapy and Oncology, K. S. Hegde Medical Academy, Mangalore, Karnataka, India.
Ann Afr Med. 2020 Apr-Jun;19(2):144-146. doi: 10.4103/aam.aam_33_19.
Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms of fibroblastic origin. They commonly arise from visceral pleura, but also arise from nonserosal sites such as meninges, central nervous system parenchyma, and spinal cord. In the spinal cord, SFTs commonly arise from the thoracic spinal cord, followed by cervical spinal cord, lumbar spinal cord, and sacrum. Histologically, SFTs can be similar to hemangiopericytoma, schwannoma, fibrous meningioma, fibroma, gliofibroma, and ependymoma. Immunohistochemistry (IHC) plays an important role in differentiating SFTs from other identical tumors. Here, we report a rare case of SFT of the cervical spinal cord, which was initially reported as hemangiopericytoma, and the diagnosis of SFT was confirmed by IHC.
孤立性纤维性肿瘤(SFTs)是一种罕见的起源于成纤维细胞的间叶性肿瘤。它们通常起源于脏层胸膜,但也可起源于非浆膜部位,如脑膜、中枢神经系统实质和脊髓。在脊髓中,SFTs通常起源于胸段脊髓,其次是颈段脊髓、腰段脊髓和骶骨。在组织学上,SFTs可类似于血管外皮细胞瘤、神经鞘瘤、纤维性脑膜瘤、纤维瘤、神经胶质纤维瘤和室管膜瘤。免疫组织化学(IHC)在鉴别SFTs与其他相似肿瘤方面起着重要作用。在此,我们报告一例罕见的颈段脊髓SFT,最初被报告为血管外皮细胞瘤,通过免疫组织化学确诊为SFT。