A Novel, Multi-Faceted Perception of Lactate in Neurology.
作者信息
Mason Shayne
机构信息
Human Metabolomics, North-West University, Potchefstroom, South Africa.
出版信息
Front Neurosci. 2020 May 15;14:460. doi: 10.3389/fnins.2020.00460. eCollection 2020.
Abstract
摘要
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Mol Neurobiol. 2020 Apr;57(4):2021-2037. doi: 10.1007/s12035-019-01863-8. Epub 2020 Jan 8.
2
Lactate and pyruvate promote oxidative stress resistance through hormetic ROS signaling.乳酸盐和丙酮酸通过有益的 ROS 信号促进氧化应激抗性。
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Contribution of astrocytes to metabolic dysfunction in the Alzheimer's disease brain.星形胶质细胞在阿尔茨海默病大脑代谢功能障碍中的作用。
Biol Chem. 2019 Aug 27;400(9):1113-1127. doi: 10.1515/hsz-2019-0140.
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J Mol Biol. 2019 Apr 19;431(9):1878-1888. doi: 10.1016/j.jmb.2019.03.005. Epub 2019 Mar 13.
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Sustained elevation of cerebrospinal fluid glucose and lactate after a single seizure does not parallel with mitochondria energy production.单次癫痫发作后脑脊液葡萄糖和乳酸的持续升高与线粒体能量产生不平行。
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