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在 COVID-19 大流行期间进行的内分泌外科手术:意大利是否需要更新手术适应证?

Endocrine surgery during COVID-19 pandemic: do we need an update of indications in Italy?

机构信息

Division of Endocrine Surgery, "Agostino Gemelli" School of Medicine, University Foundation Polyclinic, Catholic University of the Sacred Heart, Rome, Italy.

Department of Translational and Precision Medicine, "Sapienza" University of Rome, Rome, Italy.

出版信息

Endocrine. 2020 Jun;68(3):485-488. doi: 10.1007/s12020-020-02357-7. Epub 2020 Jun 4.

Abstract

The ongoing spread of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a significant threat to global health. As the coronavirus outbreak began spreading, hospitals were forced to relocate resources to treat the growing number of COVID-19 patients. As a consequence, doctors across the country canceled tens of thousands of nonurgent surgeries. However, recognizing that the COVID-19 situation may be highly variable and fluid in different communities across the country, elective surgery could be still allowed in some centers for patients included in the high-priority class. The majority of endocrine disorders requiring surgical treatment in patients identifiable as first-priority class, or needing hospitalization within 30 days, are generally represented by malignant thyroid tumors, hyperthyroidism, hyperparathyroidism, and some adrenal disorders. The need for urgent intervention is evaluated on a case-by-case basis according to the severity of the symptoms, the likelihood of progression, and global clinical judgment. On the basis of the above indications, during the last 4 weeks, we performed 18 planned surgical treatments in patients with thyroid cancer (total thyroidectomies, plus lymph node dissection if needed) or multinodular toxic goiter. In no case, postoperative ventilatory support was needed, and the average hospital stay was 3 days. The negative COVID-19 status for all the treated patients was appropriately evaluated beforehand. Nobody knows how long the current COVID-19 pandemic will be lasting. Certainly, we will be requested in the next future to incrementally offer surgical services for endocrine disorders that have been deferred for the COVID-19 pandemic.

摘要

持续传播的 2019 年冠状病毒病(COVID-19)是由严重急性呼吸系统综合征冠状病毒 2 型(SARS-CoV-2)引起的,这对全球健康构成了重大威胁。随着冠状病毒的爆发开始蔓延,医院被迫重新调配资源来治疗不断增加的 COVID-19 患者。因此,全国各地的医生取消了数万例非紧急手术。然而,鉴于 COVID-19 情况在全国不同社区可能高度多变和不稳定,一些中心仍可能允许对属于高优先级类别的患者进行选择性手术。需要在 30 天内住院的患者中,属于第一优先级类别、需要手术治疗的大多数内分泌疾病,一般表现为恶性甲状腺肿瘤、甲状腺功能亢进、甲状旁腺功能亢进和一些肾上腺疾病。根据症状的严重程度、进展的可能性和全球临床判断,需要紧急干预的情况需要逐个评估。根据上述指征,在过去的 4 周内,我们对 18 例甲状腺癌患者(如果需要,则进行全甲状腺切除术加淋巴结清扫术)或多结节毒性甲状腺肿患者进行了 18 例计划中的手术治疗。在任何情况下,都不需要术后通气支持,平均住院时间为 3 天。所有接受治疗的患者的 COVID-19 检测结果均为阴性,这是在治疗前进行了适当评估的。没有人知道当前的 COVID-19 大流行将持续多久。当然,在未来的某个时候,我们将被要求逐步为因 COVID-19 大流行而推迟的内分泌疾病提供手术服务。

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