职业性石英暴露与男性个体心房颤动风险的关联。
Occupational Quartz Exposure in a Population of Male Individuals-Association With Risk of Developing Atrial Fibrillation.
机构信息
School of Medical Sciences Örebro, University, Örebro, Sweden (Mr Montén); Department of Occupational and Environmental Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden (Bryngelsson, Fornander, Mr Vihlborg); Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (Wiebert).
出版信息
J Occup Environ Med. 2020 Jun;62(6):e267-e272. doi: 10.1097/JOM.0000000000001862.
OBJECTIVE
Occupational quartz exposure is a health risk, with increased risk of developing lung, autoimmune diseases, and elevated mortality in cardiovascular diseases.
METHODS
The population was obtained from the period 2005 to 2016 and consisted of 5237 cases of patients with atrial fibrillation (AF). Quartz exposure information was obtained through a Swedish job exposure matrix.
RESULTS
The risk of developing AF was increased for the quartz-exposed male population who were within a year of having commenced employment OR 1.54; (95% CI 1.06-2.24); this increased in the age group 20 to 55 (OR 2.05; CI 95% 1.02-4.10).
CONCLUSION
Our main conclusion is that quartz dust exposure may be related to increased risk of AF in high exposed (above 0.05 mg/m mean quartz dust) in men aged 20 to 55 years.
目的
职业性石英暴露是一种健康风险，会增加患肺病、自身免疫性疾病的风险，并使心血管疾病的死亡率升高。
方法
该人群来自于 2005 年至 2016 年期间，共包括 5237 例心房颤动（AF）患者。石英暴露信息通过瑞典工作暴露矩阵获得。
结果
在开始工作的一年内，暴露于石英的男性人群患 AF 的风险增加，比值比（OR）为 1.54（95%置信区间 [CI]，1.06-2.24）；20 至 55 岁年龄组的风险增加（OR 2.05；95%CI 1.02-4.10）。
结论
我们的主要结论是，在暴露于石英粉尘（＞0.05mg/m 平均石英粉尘）的男性中，石英粉尘暴露可能与 20 至 55 岁人群中 AF 风险增加有关。
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