Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, UPM Serdang, Selangor, Malaysia.
Institute of Advanced Technology, Universiti Putra Malaysia, UPM Serdang, Selangor, Malaysia.
PLoS One. 2020 Jun 5;15(6):e0234148. doi: 10.1371/journal.pone.0234148. eCollection 2020.
In this paper, Response Surface Methodology with central composite design (RSM/CCD) was used to optimize a modified electrode for improved electron transfer rate and electrochemical performance. The modification was done on a screen-printed carbon electrode (SPCE) with reduced graphene oxide (ERGO)/calix [4] arene (ERGOC4-SPCE). The properties of the modified electrodes were analyzed via cyclic voltammetry, Raman spectroscopy, and Fourier-Transform Infrared (FT-IR) spectroscopy. Then, different variables were optimized, namely, the concentration of graphene oxide, GO (A), the number of scan cycles of graphene oxide (B), and the deposition time (C). The effect of the optimized variables on the reduction-oxidation peak current response of the potassium ferricyanide redox system was analyzed. By using statistical analysis, it shows a significant effect of the concentration of GO, the deposition time, and the number of scans cycles on the peak current response. The coefficient of determination (R2) value of 0.9987 produced indicated a good fit of the model with experimental finding.
本文采用中心复合设计响应面法（RSM/CCD）对经过改良的电极进行优化，以提高电子转移速率和电化学性能。该改良是在丝网印刷碳电极（SPCE）上进行的，使用了还原氧化石墨烯（ERGO）/杯[4]芳烃（ERGOC4-SPCE）。通过循环伏安法、拉曼光谱和傅里叶变换红外（FT-IR）光谱分析了修饰电极的性能。然后，对不同变量进行了优化，即氧化石墨烯的浓度（A）、氧化石墨烯的扫描循环次数（B）和沉积时间（C）。分析了优化变量对铁氰化钾氧化还原体系还原-氧化峰电流响应的影响。通过统计分析，表明 GO 浓度、沉积时间和扫描循环次数对峰电流响应有显著影响。得出的决定系数（R2）值为 0.9987，表明模型与实验结果拟合良好。
