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How community vulnerability factors jointly affect multiple health outcomes after catastrophic storms.社区脆弱性因素如何共同影响灾难性风暴后的多种健康结果。
Environ Int. 2020 Jan;134:105285. doi: 10.1016/j.envint.2019.105285. Epub 2019 Nov 11.
2
Short-term effects of ambient air pollution on chronic obstructive pulmonary disease admissions in Beijing, China (2013-2017).中国北京地区环境空气污染对慢性阻塞性肺疾病住院率的短期影响(2013 - 2017年)
Int J Chron Obstruct Pulmon Dis. 2019 Jan 23;14:297-309. doi: 10.2147/COPD.S188900. eCollection 2019.
3
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4
IL-33 induced inflammation exacerbated the development of chronic obstructive pulmonary disease through oxidative stress.IL-33 通过氧化应激诱导的炎症加重慢性阻塞性肺疾病的发展。
Eur Rev Med Pharmacol Sci. 2018 Mar;22(6):1758-1764. doi: 10.26355/eurrev_201803_14593.
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Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort.农村居住与慢性阻塞性肺疾病急性加重。SPIROMICS队列分析。
Ann Am Thorac Soc. 2018 Jul;15(7):808-816. doi: 10.1513/AnnalsATS.201710-837OC.
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Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary.慢性阻塞性肺疾病全球策略:诊断、管理与预防 2017 年报告。GOLD 执行摘要。
Am J Respir Crit Care Med. 2017 Mar 1;195(5):557-582. doi: 10.1164/rccm.201701-0218PP.
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The exposure-response relationship between temperature and childhood hand, foot and mouth disease: A multicity study from mainland China.温度与儿童手足口病暴露-反应关系的多城市研究:来自中国大陆。
Environ Int. 2017 Mar;100:102-109. doi: 10.1016/j.envint.2016.11.021. Epub 2017 Jan 6.
8
Major air pollutants and risk of COPD exacerbations: a systematic review and meta-analysis.主要空气污染物与慢性阻塞性肺疾病急性加重风险:一项系统评价与荟萃分析
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Respiratory Effects of Indoor Heat and the Interaction with Air Pollution in Chronic Obstructive Pulmonary Disease.室内高温对慢性阻塞性肺疾病的呼吸影响及其与空气污染的相互作用
Ann Am Thorac Soc. 2016 Dec;13(12):2125-2131. doi: 10.1513/AnnalsATS.201605-329OC.
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Temperature Variability and Mortality: A Multi-Country Study.温度变异性与死亡率:一项多国研究。
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停电:COPD 加重的一个被忽视的风险因素。

Power Outage: An Ignored Risk Factor for COPD Exacerbations.

机构信息

Department of Environmental Health Sciences, University at Albany, State University of New York, Rensselaer, NY.

Department of Geography, Kent State University, Kent, OH.

出版信息

Chest. 2020 Dec;158(6):2346-2357. doi: 10.1016/j.chest.2020.05.555. Epub 2020 Jun 2.

DOI:10.1016/j.chest.2020.05.555
PMID:32502591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7768937/
Abstract

BACKGROUND

COPD is the third leading cause of death in the United States, with 16 million Americans currently experiencing difficulty with breathing. Power outages could be life-threatening for those relying on electricity. However, significant gaps remain in understanding the potential impact of power outages on COPD exacerbations.

RESEARCH QUESTION

The goal of this study was to determine how power outages affect COPD exacerbations.

STUDY DESIGN AND METHODS

Using distributed lag nonlinear models controlling for time-varying confounders, the hospitalization rate during a power outage was compared vs non-outage periods to determine the rate ratio (RR) for COPD and its subtypes at each of 0 to 6 lag days in New York State from 2001 to 2013. Stratified analyses were conducted according to sociodemographic characteristics, season, and clinical severity; changes were investigated in numerous critical medical indicators, including length of stay, hospital cost, the number of comorbidities, and therapeutic procedures between the two periods.

RESULTS

The RR of COPD hospitalization following power outages ranged from 1.03 to 1.39 across lag days. The risk was strongest at lag and lag days and lasted significantly for 7 days. Associations were stronger for the subgroup with acute bronchitis (RR, 1.08-1.69) than for cases of acute exacerbation (RR, 1.03-1.40). Compared with non-outage periods, the outage period was observed to be $4.67 thousand greater in hospital cost and 1.38 greater in the number of comorbidities per case. The average cost (or number of comorbidities) was elevated in all groups stratified according to cost (or number of comorbidities). In contrast, changes in the average length of stay (-0.43 day) and the average number of therapeutic procedures (-0.09) were subtle.

INTERPRETATION

Power outages were associated with a significantly elevated rate of COPD hospitalization, as well as greater costs and number of comorbidities. The average cost and number of comorbidities were elevated in all clinical severity groups.

摘要

背景

在美国,COPD 是导致死亡的第三大原因,目前有 1600 万美国人呼吸困难。对于依赖电力的人来说,停电可能会危及生命。然而,对于停电对 COPD 恶化的潜在影响,人们的认识仍存在显著差距。

研究问题

本研究旨在确定停电如何影响 COPD 恶化。

研究设计与方法

本研究使用分布滞后非线性模型,控制随时间变化的混杂因素,比较了纽约州 2001 年至 2013 年期间停电期间与非停电期间的住院率,以确定每个滞后 0 至 6 天的 COPD 及其亚型的发病率比值(RR)。根据社会人口统计学特征、季节和临床严重程度进行分层分析;在两个时期之间,调查了许多关键医疗指标的变化,包括住院时间、住院费用、合并症数量和治疗程序。

结果

停电后 COPD 住院的 RR 在滞后天数范围内为 1.03 至 1.39。在滞后和滞后天数的风险最强,并且持续显著 7 天。在急性支气管炎亚组(RR,1.08-1.69)的关联强于急性加重(RR,1.03-1.40)。与非停电期相比,停电期的住院费用增加了 4670 美元,每例合并症的数量增加了 1.38。根据成本(或合并症数量)分层的所有组中,平均成本(或合并症数量)均升高。相比之下,平均住院时间(-0.43 天)和平均治疗程序(-0.09)的变化很小。

解释

停电与 COPD 住院率显著升高有关,同时还增加了成本和合并症数量。所有临床严重程度组的平均成本和合并症数量均升高。