Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao PDR; Myanmar Oxford Clinical Research Unit, Yangon, Myanmar; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Myanmar Oxford Clinical Research Unit, Yangon, Myanmar; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Infectious Diseases Data Observatory (IDDO), Centre for Tropical Medicine and Global Health, University of Oxford, UK.
Int J Infect Dis. 2020 Aug;97:60-65. doi: 10.1016/j.ijid.2020.05.121. Epub 2020 Jun 2.
A priority-setting process (PSP) was launched to define priorities for patient-centered antimicrobial resistance (AMR) surveillance and research in low- and middle-income countries (LMICs). A list of uncertainties related to AMR surveillance in human health was generated using an online survey of stakeholders in LMICs, which asked for unanswered questions about diagnosis, treatment, or prevention of antibiotic resistance.
A total of 445 respondents generated 1076 questions that were mapped to a final shortlist of 107 questions. The most common theme was the treatment of drug-resistant infections, followed by diagnosis, then prevention, and requests for local AMR data. The most asked question was a request for local AMR data, revealing the lack of basic information in many LMICs to guide actions to tackle AMR. The steering group recommended three research areas to be prioritized for funding in the next five years: infection prevention and control in LMICs, improved electronic patient records, starting with laboratory information management systems, and sustainable behavior change among doctors and other health care professionals with a focus on diagnostic stewardship.
启动了一项优先事项设定流程 (PSP)，以确定以患者为中心的抗微生物药物耐药性 (AMR) 监测和研究在中低收入国家 (LMICs) 的优先事项。使用在线调查，向 LMICs 的利益相关者询问有关 AMR 诊断、治疗或预防的未解决问题，从而生成了与人类健康中的 AMR 监测相关的一系列不确定性列表。
共有 445 名受访者提出了 1076 个问题，这些问题被映射到最终的 107 个简短问题列表中。最常见的主题是耐药感染的治疗，其次是诊断，然后是预防，以及对当地 AMR 数据的请求。询问最多的问题是请求当地 AMR 数据，这表明许多 LMICs 缺乏基本信息来指导应对 AMR 的行动。指导小组建议在未来五年内优先为三个研究领域提供资金：LMICs 的感染预防和控制、改进电子患者记录，首先从实验室信息管理系统开始，以及重点是诊断管理的医生和其他医疗保健专业人员的可持续行为改变。
