Tsai Ming-Tzu, He Rong-Ting, Huang Heng-Li, Tu Ming-Gene, Hsu Jui-Ting
Department of Biomedical Engineering, Hungkuang University, Taichung 433, Taiwan.
School of Dentistry, China Medical University, Taichung 404, Taiwan.
Diagnostics (Basel). 2020 Jun 3;10(6):368. doi: 10.3390/diagnostics10060368.
Assessing bone quality and quantity at the location of dental implants before dental implantation is crucial. In recent years, dental cone-beam computed tomography (dental CBCT) has often been used to assess bone quality and quantity prior to dental implant. However, the effect of scanning resolution on the prediction of trabecular bone microarchitectural parameters (TBMPs) remains unclear. The objective of this study was to examine how dental CBCT with various scanning resolution differs with regard to predicting TBMPs. This study used micro-computed tomography (micro-CT) with 18 μm resolution and dental CBCT with 100 μm and 150 μm resolutions on 28 fresh bovine vertebrae cancellous bone specimens. Subsequently, all images were input into the ImageJ software to measure four TBMPs: bone volume total volume fraction (BV/TV), trabecular thickness (Tb.Th), trabecular number (Tb.N), and trabecular separation (Tb.Sp). One-way analysis of variance and Tukey's test were subsequently used to assess the differences between three scanning modes for the four TBMPs. In addition, correlations between measurement results obtained from micro-CT and dental CBCT with two resolutions were measured. The experimental results indicated that significant differences in four TBMPs were observed between micro-CT and dental CBCT ( < 0.05). The correlation coefficients between BV/TV, Tb.N, and Tb.Sp obtained from micro-CT and from dental CBCT with 100 μm resolution (0.840, 0.739, and 0.820, respectively) were greater than the correlation coefficients between BV/TV, Tb.N, and Tb.Sp obtained from micro-CT and from dental CBCT with 150 μm resolution (0.758, 0.367, and 0.724, respectively). The experimental results revealed that the TBMPs measured with dental CBCT with two resolutions differed from ideal values, but a higher resolution could provide more accurate prediction results, particularly for BV/TV, Tb.N, and Tb.Sp.
在种植牙植入前评估种植牙位置的骨质量和骨量至关重要。近年来,牙科锥形束计算机断层扫描(牙科CBCT)经常被用于在种植牙植入前评估骨质量和骨量。然而,扫描分辨率对小梁骨微结构参数(TBMPs)预测的影响仍不清楚。本研究的目的是研究具有不同扫描分辨率的牙科CBCT在预测TBMPs方面有何不同。本研究对28个新鲜牛椎骨松质骨标本使用了分辨率为18μm的微型计算机断层扫描(微型CT)以及分辨率为100μm和150μm的牙科CBCT。随后,将所有图像输入ImageJ软件以测量四个TBMPs:骨体积总体积分数(BV/TV)、小梁厚度(Tb.Th)、小梁数量(Tb.N)和小梁间距(Tb.Sp)。随后使用单因素方差分析和Tukey检验来评估四种TBMPs在三种扫描模式之间的差异。此外,还测量了微型CT与两种分辨率牙科CBCT获得的测量结果之间的相关性。实验结果表明,微型CT和牙科CBCT之间在四种TBMPs上观察到显著差异(<0.05)。微型CT与分辨率为100μm的牙科CBCT获得的BV/TV、Tb.N和Tb.Sp之间的相关系数(分别为0.840、0.739和0.820)大于微型CT与分辨率为150μm的牙科CBCT获得的BV/TV、Tb.N和Tb.Sp之间的相关系数(分别为0.758、0.367和0.724)。实验结果表明,用两种分辨率的牙科CBCT测量的TBMPs与理想值不同,但更高的分辨率可以提供更准确的预测结果,特别是对于BV/TV、Tb.N和Tb.Sp。