Breast Unit - Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy.
Breast Unit - Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy
In Vivo. 2020 Jun;34(3 Suppl):1651-1659. doi: 10.21873/invivo.11957.
BACKGROUND/AIM: Coronavirus-19 (COVID-19) pandemic outbreak is currently having a huge impact on medical resource allocation. Breast Cancer (BC) patients are concerned both with BC treatment and COVID-19. This study aimed to estimate the impact of anxiety among patients, caused by the spreading of COVID-19.
Between the 16th of January and the 20th of March 2020, we retrospectively enrolled 160 patients. Eighty-two patients with a suspected breast lesion (SBL) were divided into two groups: PRE-COVID-19-SBL and POST-COVID-19-SBL. Seventy-eight BC patients were divided into PRE-COVID-19-BC and POST-COVID-19-BC. Patient characteristics including age, marital status, SBL/BC diameter, personal and family history of BC, clinical stage and molecular subtype were recorded. Procedure Refusal (PR) and Surgical Refusal (SR) were also recorded with their reason.
BC and SBL analysis showed no difference in pre-treatment characteristics (p>0.05). Both POST-COVID-19-SBL and POST-COVID-19-BC groups showed higher rates of PR and SR (p=0.0208, p=0.0065 respectively). Infection risk represented primary reason for refusal among POST-COVID-19 patients.
COVID-19-related anxiety could affect patients' decision-making process.
背景/目的：目前，冠状病毒-19（COVID-19）大流行对医疗资源配置产生了巨大影响。乳腺癌（BC）患者不仅关心 BC 的治疗，也关心 COVID-19。本研究旨在评估 COVID-19 传播引起的患者焦虑对患者的影响。
在 2020 年 1 月 16 日至 3 月 20 日期间，我们回顾性地招募了 160 名患者。82 名疑似乳腺病变（SBL）患者分为两组：COVID-19 前 SBL 组和 COVID-19 后 SBL 组。78 名 BC 患者分为 COVID-19 前 BC 组和 COVID-19 后 BC 组。记录了患者的特征，包括年龄、婚姻状况、SBL/BC 直径、BC 的个人和家族史、临床分期和分子亚型。还记录了程序拒绝（PR）和手术拒绝（SR）及其原因。
BC 和 SBL 分析显示，治疗前特征无差异（p>0.05）。COVID-19 后 SBL 和 COVID-19 后 BC 组的 PR 和 SR 发生率更高（p=0.0208，p=0.0065）。感染风险是 COVID-19 患者拒绝治疗的主要原因。
COVID-19 相关的焦虑可能会影响患者的决策过程。
