新型冠状病毒病 2019（COVID-19）的临床特征综述。
Review of the Clinical Characteristics of Coronavirus Disease 2019 (COVID-19).
机构信息
Department of Anesthesiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China.
Department of Critical Care Medicine, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
出版信息
J Gen Intern Med. 2020 May;35(5):1545-1549. doi: 10.1007/s11606-020-05762-w. Epub 2020 Mar 4.
Abstract
In late December 2019, a cluster of cases with 2019 Novel Coronavirus pneumonia (SARS-CoV-2) in Wuhan, China, aroused worldwide concern. Previous studies have reported epidemiological and clinical characteristics of coronavirus disease 2019 (COVID-19). The purpose of this brief review is to summarize those published studies as of late February 2020 on the clinical features, symptoms, complications, and treatments of COVID-19 and help provide guidance for frontline medical staff in the clinical management of this outbreak.
摘要
2019 年 12 月下旬，中国武汉发生了一组新型冠状病毒肺炎（SARS-CoV-2）病例，引起了全球关注。先前的研究报告了 2019 年冠状病毒病（COVID-19）的流行病学和临床特征。本简要综述的目的是总结截至 2020 年 2 月下旬发表的关于 COVID-19 的临床特征、症状、并发症和治疗的研究，为一线医务人员在本次疫情的临床管理中提供指导。
相似文献
1
Review of the Clinical Characteristics of Coronavirus Disease 2019 (COVID-19).新型冠状病毒病 2019（COVID-19）的临床特征综述。
J Gen Intern Med. 2020 May;35(5):1545-1549. doi: 10.1007/s11606-020-05762-w. Epub 2020 Mar 4.
2
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) infection during late pregnancy: a report of 18 patients from Wuhan, China.严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）在妊娠晚期感染：来自中国武汉的 18 例患者报告。
BMC Pregnancy Childbirth. 2020 Jul 8;20(1):394. doi: 10.1186/s12884-020-03026-3.
3
Clinical characteristics of 54 medical staff with COVID-19: A retrospective study in a single center in Wuhan, China.54 例医务人员 COVID-19 临床特征回顾性研究：中国武汉单中心研究。
J Med Virol. 2020 Jul;92(7):807-813. doi: 10.1002/jmv.25793. Epub 2020 Apr 6.
4
The outbreak of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): A review of the current global status.新型严重急性呼吸系统综合症冠状病毒 2（SARS-CoV-2）的爆发：当前全球状况综述。
J Infect Public Health. 2020 Nov;13(11):1601-1610. doi: 10.1016/j.jiph.2020.07.011. Epub 2020 Aug 4.
5
The implications of preliminary screening and diagnosis: Clinical characteristics of 33 mild patients with SARS-CoV-2 infection in Hunan, China.初步筛查和诊断的意义：中国湖南 33 例 SARS-CoV-2 感染轻症患者的临床特征。
J Clin Virol. 2020 Jul;128:104397. doi: 10.1016/j.jcv.2020.104397. Epub 2020 Apr 30.
6
Correlation between the migration scale index and the number of new confirmed coronavirus disease 2019 cases in China.中国新型冠状病毒病新增确诊病例数与迁移规模指数的相关性。
Epidemiol Infect. 2020 May 19;148:e99. doi: 10.1017/S0950268820001119.
7
Coronavirus Disease 2019: Coronaviruses and Blood Safety.2019 年冠状病毒病：冠状病毒与血液安全。
Transfus Med Rev. 2020 Apr;34(2):75-80. doi: 10.1016/j.tmrv.2020.02.003. Epub 2020 Feb 21.
8
Coronavirus disease 2019 (COVID-19): A literature review.新型冠状病毒病 2019（COVID-19）：文献综述。
J Infect Public Health. 2020 May;13(5):667-673. doi: 10.1016/j.jiph.2020.03.019. Epub 2020 Apr 8.
9
The First 75 Days of Novel Coronavirus (SARS-CoV-2) Outbreak: Recent Advances, Prevention, and Treatment.新型冠状病毒（SARS-CoV-2）爆发的前 75 天：最新进展、预防和治疗。
Int J Environ Res Public Health. 2020 Mar 30;17(7):2323. doi: 10.3390/ijerph17072323.
10
Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2.新型冠状病毒 2019 年 SARS-CoV-2 患者的影像学和临床特征。
Eur J Nucl Med Mol Imaging. 2020 May;47(5):1275-1280. doi: 10.1007/s00259-020-04735-9. Epub 2020 Feb 28.
引用本文的文献
1
Long-term cardiovascular outcomes after exercise-based cardiac rehabilitation among coronavirus disease 2019 survivors: A nationwide cohort study.2019冠状病毒病幸存者运动心脏康复后的长期心血管结局：一项全国性队列研究。
Tzu Chi Med J. 2025 Jun 5;37(3):293-298. doi: 10.4103/tcmj.tcmj_154_24. eCollection 2025 Jul-Sep.
2
COVID-19 management in patients with comorbid conditions.合并症患者的 COVID-19 管理。
World J Virol. 2025 Jun 25;14(2):102674. doi: 10.5501/wjv.v14.i2.102674.
3
Impact of the COVID-19 Pandemic on Seizure Control in Pediatric Epilepsy: Risk Factors and Clinical Outcomes.2019年冠状病毒病大流行对小儿癫痫发作控制的影响：危险因素及临床结局
Healthcare (Basel). 2025 Jan 16;13(2):172. doi: 10.3390/healthcare13020172.
4
Using Large Language Models to Retrieve Critical Data from Clinical Processes and Business Rules.使用大语言模型从临床流程和业务规则中检索关键数据。
Bioengineering (Basel). 2024 Dec 28;12(1):17. doi: 10.3390/bioengineering12010017.
5
Apoptotic Vesicles Attenuate Acute Lung Injury CD73-Mediated Inhibition of Platelet Activation and NETosis.凋亡小泡减轻急性肺损伤：CD73介导的血小板活化和中性粒细胞胞外陷阱形成的抑制作用
Int J Nanomedicine. 2025 Jan 4;20:91-107. doi: 10.2147/IJN.S485012. eCollection 2025.
6
Strategies to Overcome Erroneous Outcomes in Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Testing: Insights From the COVID-19 Pandemic.克服逆转录聚合酶链反应（RT-PCR）检测错误结果的策略：来自COVID-19大流行的见解
Cureus. 2024 Nov 3;16(11):e72954. doi: 10.7759/cureus.72954. eCollection 2024 Nov.
7
Role of the receptor for advanced glycation end products in the severity of SARS-CoV-2 infection in diabetic patients.晚期糖基化终末产物受体在糖尿病患者感染严重急性呼吸综合征冠状病毒2中的作用。
Diabetol Int. 2024 Jul 26;15(4):732-744. doi: 10.1007/s13340-024-00746-1. eCollection 2024 Oct.
8
Investigation of the Relationship between Vitamin D Deficiency and Vitamin D-Binding Protein Polymorphisms in Severe COVID-19 Patients.重症 COVID-19 患者维生素 D 缺乏与维生素 D 结合蛋白多态性之间关系的研究。
Diagnostics (Basel). 2024 Sep 3;14(17):1941. doi: 10.3390/diagnostics14171941.
9
Longitudinal assessment of the impact of COVID-19 infection on mask-wearing behaviors.新冠病毒感染对戴口罩行为影响的纵向评估。
BMC Public Health. 2024 Aug 16;24(1):2230. doi: 10.1186/s12889-024-19776-0.
10
Comprehensive Review of COVID-19: Epidemiology, Pathogenesis, Advancement in Diagnostic and Detection Techniques, and Post-Pandemic Treatment Strategies.新型冠状病毒肺炎（COVID-19）的全面综述：流行病学、发病机制、诊断和检测技术的进展，以及大流行后的治疗策略。
Int J Mol Sci. 2024 Jul 26;25(15):8155. doi: 10.3390/ijms25158155.
本文引用的文献
1
Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records.九名孕妇感染 COVID-19 的临床特征和宫内垂直传播潜力：病历回顾性研究。
Lancet. 2020 Mar 7;395(10226):809-815. doi: 10.1016/S0140-6736(20)30360-3. Epub 2020 Feb 12.
2
Evidence of SARS-CoV-2 Infection in Returning Travelers from Wuhan, China.从中国武汉返回的旅行者中新型冠状病毒感染的证据。
N Engl J Med. 2020 Mar 26;382(13):1278-1280. doi: 10.1056/NEJMc2001899. Epub 2020 Feb 18.
3
Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province.湖北省三级医院新型冠状病毒病例的临床特征。
Chin Med J (Engl). 2020 May 5;133(9):1025-1031. doi: 10.1097/CM9.0000000000000744.
4
2019-nCoV transmission through the ocular surface must not be ignored.2019新型冠状病毒通过眼表的传播不容忽视。
Lancet. 2020 Feb 22;395(10224):e39. doi: 10.1016/S0140-6736(20)30313-5. Epub 2020 Feb 6.
5
Baricitinib as potential treatment for 2019-nCoV acute respiratory disease.巴瑞替尼作为2019新型冠状病毒急性呼吸道疾病的潜在治疗方法。
Lancet. 2020 Feb 15;395(10223):e30-e31. doi: 10.1016/S0140-6736(20)30304-4. Epub 2020 Feb 4.
6
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.《武汉 2019 年新型冠状病毒感染的肺炎 138 例住院患者临床特征分析》
JAMA. 2020 Mar 17;323(11):1061-1069. doi: 10.1001/jama.2020.1585.
7
[Analysis of clinical features of 29 patients with 2019 novel coronavirus pneumonia].[29例2019新型冠状病毒肺炎患者临床特征分析]
Zhonghua Jie He He Hu Xi Za Zhi. 2020 Feb 6;43(0):E005. doi: 10.3760/cma.j.issn.1001-0939.2020.0005.
8
A pneumonia outbreak associated with a new coronavirus of probable bat origin.一种新型冠状病毒引发的肺炎疫情，该病毒可能来源于蝙蝠。
Nature. 2020 Mar;579(7798):270-273. doi: 10.1038/s41586-020-2012-7. Epub 2020 Feb 3.
9
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.中国武汉 99 例 2019 年新型冠状病毒肺炎患者的流行病学和临床特征：描述性研究。
Lancet. 2020 Feb 15;395(10223):507-513. doi: 10.1016/S0140-6736(20)30211-7. Epub 2020 Jan 30.
10
First Case of 2019 Novel Coronavirus in the United States.美国首例 2019 新型冠状病毒病例。
N Engl J Med. 2020 Mar 5;382(10):929-936. doi: 10.1056/NEJMoa2001191. Epub 2020 Jan 31.
Zotero 插件