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植物中核酸介导的病原体相关分子模式触发的免疫反应

Nucleic acid-mediated PAMP-triggered immunity in plants.

作者信息

Amari Khalid, Niehl Annette

机构信息

Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH, Inhoffenstraße 7B, 38124 Braunschweig, Germany.

Julius Kühn-Institut, Federal Research Centre for Cultivated Plants, Institute for Epidemiology and Pathogen Diagnostics, Messeweg 11-12, 38102 Braunschweig, Germany.

出版信息

Curr Opin Virol. 2020 Jun;42:32-39. doi: 10.1016/j.coviro.2020.04.003. Epub 2020 Jun 3.

Abstract

With the discovery that pattern-triggered immunity (PTI) is active against virus infection in plants less than a decade ago, we began to understand that antiviral immunity goes far beyond RNA silencing and resistance gene-mediated immunity and is much more complex than previously thought. Since then, receptor kinases, signaling components and outputs, and viral suppressors of PTI were discovered and double-stranded RNAs as well as possibly other viral nucleic acids identified as candidates for viral pathogen-associated molecular patterns (PAMPs) in plants. Here, we summarize recent progress in PAMP-triggered antiviral immunity in plants and discuss possible crosstalk between dsRNA-triggered defense pathways.

摘要

不到十年前,随着模式触发免疫(PTI)对植物病毒感染具有活性这一发现,我们开始明白抗病毒免疫远不止RNA沉默和抗性基因介导的免疫,而且比之前认为的要复杂得多。从那时起,受体激酶、信号转导组分和输出以及PTI的病毒抑制因子被发现,双链RNA以及可能的其他病毒核酸被鉴定为植物中病毒病原体相关分子模式(PAMP)的候选物。在这里,我们总结了植物中PAMP触发的抗病毒免疫的最新进展,并讨论了双链RNA触发的防御途径之间可能存在的串扰。

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