Amari Khalid, Niehl Annette
Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH, Inhoffenstraße 7B, 38124 Braunschweig, Germany.
Julius Kühn-Institut, Federal Research Centre for Cultivated Plants, Institute for Epidemiology and Pathogen Diagnostics, Messeweg 11-12, 38102 Braunschweig, Germany.
Curr Opin Virol. 2020 Jun;42:32-39. doi: 10.1016/j.coviro.2020.04.003. Epub 2020 Jun 3.
With the discovery that pattern-triggered immunity (PTI) is active against virus infection in plants less than a decade ago, we began to understand that antiviral immunity goes far beyond RNA silencing and resistance gene-mediated immunity and is much more complex than previously thought. Since then, receptor kinases, signaling components and outputs, and viral suppressors of PTI were discovered and double-stranded RNAs as well as possibly other viral nucleic acids identified as candidates for viral pathogen-associated molecular patterns (PAMPs) in plants. Here, we summarize recent progress in PAMP-triggered antiviral immunity in plants and discuss possible crosstalk between dsRNA-triggered defense pathways.
不到十年前，随着模式触发免疫（PTI）对植物病毒感染具有活性这一发现，我们开始明白抗病毒免疫远不止RNA沉默和抗性基因介导的免疫，而且比之前认为的要复杂得多。从那时起，受体激酶、信号转导组分和输出以及PTI的病毒抑制因子被发现，双链RNA以及可能的其他病毒核酸被鉴定为植物中病毒病原体相关分子模式（PAMP）的候选物。在这里，我们总结了植物中PAMP触发的抗病毒免疫的最新进展，并讨论了双链RNA触发的防御途径之间可能存在的串扰。
