Li Hongjuan, Huang Haoming, Long Wenjie, Zuo Junling, Huang Hongqiang
The First Comprehensive Department, The Second Affiliated Hospital, Guangzhou University of Chinese Medicine (Guangdong Province Hospital of Chinese Medicine), Guangzhou, Guangdong, 510120, China.
The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510405, China; Department of Radiology, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510405, China.
Explore (NY). 2021 May-Jun;17(3):247-251. doi: 10.1016/j.explore.2020.05.009. Epub 2020 May 24.
Facioscapulohumeral muscular dystrophy (FSHD) is a common muscular disorder. At present, treatments for FSHD have limited effects on the muscle function of patients. A famous Chinese medicine formula, Buzhong Yiqi (BZYQ), has shown promising effects on several muscular diseases, but evidence regarding its effect on FSHD is lacking. This study aimed to examine the effect of BZYQ on FSHD.
A 15-year-old girl suffered from progressive muscle weakness, with a genetically confirmed diagnosis of FSHD. Except for routine FSHD management, the patient received BZQY every day. The muscle strength of the patient remarkably increased after discharge.
This study was novel in reporting a significant improvement in muscle function in a patient with FSHD treated with an integrated approach of BZYQ and routine management. Therefore, BZYQ might be a potential treatment for FSHD, requiring further investigations.
面肩肱型肌营养不良症（FSHD）是一种常见的肌肉疾病。目前，针对FSHD的治疗对患者肌肉功能的影响有限。一种著名的中药方剂补中益气汤（BZYQ）已在几种肌肉疾病中显示出有前景的疗效，但缺乏其对FSHD疗效的证据。本研究旨在探讨补中益气汤对FSHD的影响。
一名15岁女孩患有进行性肌无力，经基因确诊为FSHD。除了常规的FSHD管理外，患者每天服用补中益气汤。出院后患者的肌肉力量显著增加。
本研究首次报道了采用补中益气汤与常规管理相结合的方法治疗FSHD患者后肌肉功能有显著改善。因此，补中益气汤可能是FSHD的一种潜在治疗方法，需要进一步研究。
