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老年男性良性前列腺增生合并 COVID-19 患者的临床特征和转归:一项回顾性研究 18 例。

Clinical features and outcomes of COVID-19 patients with benign prostatic hyperplasia in ageing male: A retrospective study of 18 cases.

机构信息

Department of Urology, Haydarpasa Numune Research and Training Hospital, Istanbul, Turkey.

Department of Urology, Sultanbeyli State Hospital, Istanbul, Turkey.

出版信息

Int J Clin Pract. 2020 Aug;74(8):e13574. doi: 10.1111/ijcp.13574. Epub 2020 Jun 23.

Abstract

AIM

A worldwide pandemic of coronavirus disease 2019 (COVID-19) which emerged in China in December 2019 affects the world very seriously. We aimed to evaluate the benign prostatic hyperplasia (BPH) patients who were admitted and treated to our hospital due to COVID-19.

METHODS

Between March 18, 2020 and April 5, 2020, 18 patients admitted with COVID-19 who has BPH and are using medication for this were included in the study and analysed retrospectively. Diagnosis was confirmed by COVID-19 nucleic acid test by sampling sputum or nasopharyngeal swab. Standard COVID-19 treatment protocol determined by our Ministry of Health was applied to all patients according to their risk groups. Epidemiological, clinical, radiological features, additional diseases, laboratory tests, complications and outcome data of all patients were recorded.

RESULTS

Mean age of patients was 59.6 (range: 56-73). As the mode of transmission, 10 (55.5%) of patients were infected in hospital, 5 (27.7%) patients had a relative with COVID-19 and three (16.6%) was unknown. During follow-up, 2 (11.1%) patients were transferred to intensive care unit (ICU). One of these patients dramatically progressed and died. Patients who survived and were not transferred to ICU had lesser comorbidities and were relatively young. Mean duration of hospitalisation was 14.2 days (range 12-19).

CONCLUSION

We think that COVID-19 patients with BPH had a low mortality rate and did not have a poor prognosis in this patient group. It is crucial to take comprehensive preventive measures to control COVID-19 transmission via hospital route.

摘要

目的

2019 年 12 月在中国出现的 2019 年冠状病毒病(COVID-19)全球大流行对世界造成了严重影响。我们旨在评估因 COVID-19 而入院和接受治疗的良性前列腺增生(BPH)患者。

方法

2020 年 3 月 18 日至 4 月 5 日,共纳入 18 例因 COVID-19 入院且正在使用药物治疗的 BPH 患者进行回顾性分析。通过采集痰或鼻咽拭子进行 COVID-19 核酸检测来确诊。所有患者均按照卫生部确定的标准 COVID-19 治疗方案进行治疗,并根据其风险组进行相应的治疗。记录所有患者的流行病学、临床、影像学特征、合并症、实验室检查、并发症和转归数据。

结果

患者的平均年龄为 59.6 岁(范围:56-73 岁)。传播途径中,10 例(55.5%)患者在医院感染,5 例(27.7%)患者有 COVID-19 亲属,3 例(16.6%)原因不明。在随访期间,2 例(11.1%)患者转至重症监护病房(ICU)。其中 1 例患者病情急剧恶化并死亡。存活且未转至 ICU 的患者合并症较少且相对年轻。患者的平均住院时间为 14.2 天(范围 12-19 天)。

结论

我们认为,BPH 合并 COVID-19 的患者死亡率较低,在该患者群体中预后良好。通过综合预防措施来控制医院内 COVID-19 的传播至关重要。

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