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70 岁以上 ICU 收治标准的手术患者衰弱对结局的影响。

Influence of frailty in the outcome of surgical patients over 70 years old with admission criteria in ICU.

机构信息

Hospital Universitario Miguel Servet, Zaragoza, España.

Hospital Universitario Miguel Servet, Zaragoza, España.

出版信息

Cir Esp (Engl Ed). 2021 Jan;99(1):41-48. doi: 10.1016/j.ciresp.2020.04.022. Epub 2020 Jun 2.

Abstract

INTRODUCTION

Frailty degree can influence more than age or severity in the outcome of patients older than 70 years undergoing surgery of the digestive system that require immediate postoperative control in the ICU.

METHODS

A prospective and observational study of patients over 70 years of age who were admitted to the surgical ICU of a third level hospital immediately after an elective or emergent surgical intervention on the digestive system from June 1, 2018 until June 1, 2019. The variables age, frailty Clinical Frailty Scale (CFS), and modified Frailty Index (mFI), severity (APACHE II), type of surgery, surgical pathology were recorded upon admission. A bivariate analysis was performed to assess the influence of frailty and severity on hospital morbidity and mortality and baseline situation of the patient (in terms of dependence) at 6 months.

RESULTS

A total of 90 patients were recruited, 54.4% of whom were reoperated; 74.4% were initially discharged from the ICU, with 28.4% of readmission and directly associated to frailty (CFS and mFI: P<0.01). The overall mortality at 6 months was 44.5% being CFS (OR = 64.3; P<0.05, 95% CI: 12.3-333.9) and APACHE II (OR = 1.17; P<0.05; 95% CI: 1.04-1.32) the covariates that best related.

CONCLUSIONS

The estimation of frailty by CSF and mFI is directly associated to the surgical morbidity and readmission of elderly and severe patients admitted to the ICU. In addition, CFS and mFI has been efficient as a predictive of mortality at 6 months.

摘要

介绍

在 70 岁以上接受消化系统手术的患者中,虚弱程度可能比年龄或严重程度更能影响术后结果,这些患者需要在 ICU 进行即时术后控制。

方法

对 2018 年 6 月 1 日至 2019 年 6 月 1 日期间在三级医院接受消化系统择期或紧急手术的 70 岁以上患者进行前瞻性、观察性研究。记录入院时的变量年龄、虚弱临床虚弱量表(CFS)和改良虚弱指数(mFI)、严重程度(APACHE II)、手术类型、手术病理。进行双变量分析以评估虚弱和严重程度对医院发病率和死亡率以及患者(在依赖方面)的基线情况的影响。

结果

共招募了 90 名患者,其中 54.4%的患者再次接受手术;74.4%的患者最初从 ICU 出院,28.4%的患者再次入院,与虚弱(CFS 和 mFI:P<0.01)直接相关。6 个月时的总死亡率为 44.5%,CFS(OR=64.3;P<0.05,95%CI:12.3-333.9)和 APACHE II(OR=1.17;P<0.05;95%CI:1.04-1.32)是最佳相关的协变量。

结论

CFS 和 mFI 对虚弱的评估与 ICU 收治的老年和严重患者的手术发病率和再入院率直接相关。此外,CFS 和 mFI 能够有效地预测 6 个月时的死亡率。

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