Cardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran; Department of Community Medicine, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Cardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Complement Ther Med. 2020 Jun;51:102430. doi: 10.1016/j.ctim.2020.102430. Epub 2020 May 14.
As a popular beverage, there has been much interest in studying the effects of tea intake on hypertension (HTN), a particular risk factor for cardiovascular disorders (CVDs). We have thus aimed to isolate the randomized controlled trials investigating the efficacy of black or green tea as a beverage in subjects with elevated blood pressure (BP), or HTN.
PubMed, Scopus, Web of Science, and ProQuest dissertations and theses databases were searched from February 1, 1995, up to July 20, 2019, to identify relevant studies.
The search strategy generated 1119 trials, of which finally five trials fulfilled the criteria for being included in the current study. Three out of 5 articles showed a low risk of bias. According to nine measurements derived from 5 trials on 408 individuals, it was found that regular tea intake resulted in the reduction in SBP (weighted mean difference (WMD): -4.81 mmHg, 95 %CI: -8.40 to -1.58, P = .004) and DBP (WMD:-1.98 mmHg, 95 %CI: -3.77 to -0.20, P = .029); however, excluding the most heterogeneous trials showed that regular tea intake might reduce SBP and DBP by about -3.53 and -0.99 mmHg, respectively. Based on meta-regression findings, we found the longer the duration of tea intake (≥3months), the higher the decrease in both SBP and DBP. Categorized studies, according to the tea type, revealed that the hypotensive effects of green tea were more pronounced compared to black tea. None of the studies reported any side effects.
These results suggest the positive effects of regular tea intake on BP in subjects with elevated BP or HTN. Hence, it may be applicable to physicians, health care providers, and particularly HTN patients.
作为一种受欢迎的饮料,人们对饮茶对高血压(HTN)的影响产生了浓厚的兴趣,高血压是心血管疾病(CVDs)的一个特殊危险因素。因此,我们旨在分离出研究饮用红茶或绿茶对血压升高(BP)或 HTN 患者疗效的随机对照试验。
从 1995 年 2 月 1 日至 2019 年 7 月 20 日,检索 PubMed、Scopus、Web of Science、ProQuest 论文和论文数据库,以确定相关研究。
搜索策略产生了 1119 项试验,其中最终有 5 项试验符合纳入本研究的标准。其中 5 篇文章中有 3 篇显示出低偏倚风险。根据 5 项试验对 408 名个体的 9 项测量结果,发现定期饮茶可降低 SBP(加权均数差(WMD):-4.81mmHg,95%CI:-8.40 至-1.58,P=.004)和 DBP(WMD:-1.98mmHg,95%CI:-3.77 至-0.20,P=.029);然而,排除最具异质性的试验表明,定期饮茶可能分别使 SBP 和 DBP 降低约-3.53 和-0.99mmHg。基于荟萃回归分析结果,我们发现饮茶时间越长(≥3 个月),SBP 和 DBP 降低幅度越大。根据茶的类型对研究进行分类后发现,绿茶的降压效果比红茶更为明显。没有研究报告任何副作用。
这些结果表明,定期饮茶对血压升高或 HTN 患者的血压有积极影响。因此,它可能适用于医生、医疗保健提供者,特别是 HTN 患者。