• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Comprehensive genomic profiling of urothelial carcinoma cell lines reveals hidden research bias and caveats.

作者信息

Luo Yongwen, Ju Lingao, Wang Gang, Chen Chen, Wang Yejinpeng, Chen Liang, Zhang Yi, Xiao Yu, Wang Xinghuan

机构信息

Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.

Human Genetic Resources Preservation Center of Hubei Province, Wuhan, China.

出版信息

Clin Transl Med. 2020 Jan;10(1):294-296. doi: 10.1002/ctm2.36.

DOI:10.1002/ctm2.36
PMID:32508016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7240854/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e59/7240854/b33234531021/CTM2-10-294-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e59/7240854/b33234531021/CTM2-10-294-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e59/7240854/b33234531021/CTM2-10-294-g001.jpg

相似文献

1
Comprehensive genomic profiling of urothelial carcinoma cell lines reveals hidden research bias and caveats.尿路上皮癌细胞系的综合基因组分析揭示了潜在的研究偏差和注意事项。
Clin Transl Med. 2020 Jan;10(1):294-296. doi: 10.1002/ctm2.36.
2
Re: Comprehensive Genomic Profiling of 295 Cases of Clinically Advanced Urothelial Carcinoma of the Urinary Bladder Reveals a High Frequency of Clinically Relevant Genomic Alterations.回复：295例临床晚期膀胱尿路上皮癌的综合基因组分析揭示了临床相关基因组改变的高频率。
J Urol. 2017 Feb;197(2):319. doi: 10.1016/j.juro.2016.11.040. Epub 2016 Nov 15.
3
Re: Comprehensive Genomic Profiling of 295 Cases of Clinically Advanced Urothelial Carcinoma of the Urinary Bladder Reveals a High Frequency of Clinically Relevant Genomic Alterations.回复：对295例临床晚期膀胱尿路上皮癌进行综合基因组分析揭示了临床相关基因组改变的高频率。
Eur Urol. 2016 Aug;70(2):400-1. doi: 10.1016/j.eururo.2016.03.067. Epub 2016 Apr 18.
4
A Case Report Demonstrating the Potential Clinical Benefit of Exhaustive Molecular Profiling in an Aggressive Muscle-Invasive High-Grade Metastatic Urothelial Carcinoma.一例报告显示了详尽分子谱分析在侵袭性肌肉浸润性高级别转移性尿路上皮癌中的潜在临床益处。
Case Rep Oncol. 2017 Jun 9;10(2):493-500. doi: 10.1159/000477337. eCollection 2017 May-Aug.
5
Comprehensive genomic profiling of 295 cases of clinically advanced urothelial carcinoma of the urinary bladder reveals a high frequency of clinically relevant genomic alterations.对 295 例临床晚期膀胱癌进行全面基因组分析，揭示了临床上相关的基因组改变的高频率。
Cancer. 2016 Mar 1;122(5):702-11. doi: 10.1002/cncr.29826. Epub 2015 Dec 9.
6
Targeted DNA and RNA Sequencing of Paired Urothelial and Squamous Bladder Cancers Reveals Discordant Genomic and Transcriptomic Events and Unique Therapeutic Implications.靶向 DNA 和 RNA 测序联合分析尿路上皮癌和鳞状细胞膀胱癌揭示了不同的基因组和转录组事件以及独特的治疗意义。
Eur Urol. 2018 Dec;74(6):741-753. doi: 10.1016/j.eururo.2018.06.047. Epub 2018 Jul 20.
7
A cultured approach to canine urothelial carcinoma: molecular characterization of five cell lines.犬尿路上皮癌的培养方法：五种细胞系的分子特征分析
Canine Genet Epidemiol. 2015 Sep 17;2:15. doi: 10.1186/s40575-015-0028-3. eCollection 2015.
8
MB49 murine urothelial carcinoma: molecular and phenotypic comparison to human cell lines as a model of the direct tumor response to bacillus Calmette-Guerin.MB49小鼠尿路上皮癌：作为卡介苗直接肿瘤反应模型与人类细胞系的分子和表型比较。
J Urol. 2009 Dec;182(6):2932-7. doi: 10.1016/j.juro.2009.08.018. Epub 2009 Oct 23.
9
Distinctive differences in DNA double-strand break repair between normal urothelial and urothelial carcinoma cells.正常尿路上皮细胞和尿路上皮癌细胞在DNA双链断裂修复方面存在显著差异。
Mutat Res. 2008 Feb 1;638(1-2):56-65. doi: 10.1016/j.mrfmmm.2007.08.016. Epub 2007 Sep 5.
10
The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.UBC - 40膀胱癌细胞系索引：用于功能研究的基因组资源。
BMC Genomics. 2015 May 22;16(1):403. doi: 10.1186/s12864-015-1450-3.

引用本文的文献

1
DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC.DNA 聚合酶 POLD1 通过稳定 MYC 促进膀胱癌的增殖和转移。
Nat Commun. 2023 Apr 27;14(1):2421. doi: 10.1038/s41467-023-38160-x.
2
Translation Potential and Challenges of In Vitro and Murine Models in Cancer Clinic.癌症临床中体外和鼠类模型的转化潜力和挑战。
Cells. 2022 Nov 30;11(23):3868. doi: 10.3390/cells11233868.
3
Long-Lasting Proteinaceous Nanoformulation for Tumor Imaging and Therapy.用于肿瘤成像与治疗的长效蛋白质纳米制剂

本文引用的文献

1
Personalized Drug Sensitivity Screening for Bladder Cancer Using Conditionally Reprogrammed Patient-derived Cells.利用条件重编程的患者来源细胞进行膀胱癌个体化药物敏感性筛选。
Eur Urol. 2019 Oct;76(4):430-434. doi: 10.1016/j.eururo.2019.06.016. Epub 2019 Jun 28.
2
STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets.STRING v11：具有增强覆盖范围的蛋白质-蛋白质相互作用网络，支持在全基因组实验数据集的功能发现。
Nucleic Acids Res. 2019 Jan 8;47(D1):D607-D613. doi: 10.1093/nar/gky1131.
3
Targeted DNA and RNA Sequencing of Paired Urothelial and Squamous Bladder Cancers Reveals Discordant Genomic and Transcriptomic Events and Unique Therapeutic Implications.
ACS Omega. 2022 Aug 24;7(35):31299-31308. doi: 10.1021/acsomega.2c03561. eCollection 2022 Sep 6.
4
[Establishment of a culture system for human nasal mucosa organoids with controllable differentiation].[建立具有可控分化能力的人鼻黏膜类器官培养体系]
Nan Fang Yi Ke Da Xue Xue Bao. 2022 Jun 20;42(6):868-877. doi: 10.12122/j.issn.1673-4254.2022.06.10.
5
A novel germline EGFR variant p.R831H causes predisposition to familial CDK12-mutant prostate cancer with tandem duplicator phenotype.一种新的胚系 EGFR 变异 p.R831H 导致 CDK12 突变前列腺癌伴串联重复表型的家族易感性。
Oncogene. 2020 Oct;39(44):6871-6878. doi: 10.1038/s41388-020-01476-9. Epub 2020 Sep 25.
6
Conditional reprogramming: Modeling urological cancer and translation to clinics.条件重编程：泌尿系统癌症建模及向临床转化
Clin Transl Med. 2020 Jun;10(2):e95. doi: 10.1002/ctm2.95. Epub 2020 Jun 5.
靶向 DNA 和 RNA 测序联合分析尿路上皮癌和鳞状细胞膀胱癌揭示了不同的基因组和转录组事件以及独特的治疗意义。
Eur Urol. 2018 Dec;74(6):741-753. doi: 10.1016/j.eururo.2018.06.047. Epub 2018 Jul 20.
4
FGFR3 translocations in bladder cancer: differential sensitivity to HSP90 inhibition based on drug metabolism.膀胱癌中的FGFR3易位：基于药物代谢对HSP90抑制的差异敏感性
Mol Cancer Res. 2014 Jul;12(7):1042-54. doi: 10.1158/1541-7786.MCR-14-0004. Epub 2014 Apr 30.
5
Cell line misidentification: the beginning of the end.细胞系鉴定错误：一切的开端。
Nat Rev Cancer. 2010 Jun;10(6):441-8. doi: 10.1038/nrc2852. Epub 2010 May 7.