Department of Emergency Medicine Vanderbilt University Medical Center Nashville TN.
Department of Medicine Vanderbilt University Medical Center Nashville TN.
J Am Heart Assoc. 2020 Jun 16;9(12):e015985. doi: 10.1161/JAHA.119.015985. Epub 2020 Jun 6.
Background Emergency department (ED) visits for hypertension are rising, but the importance of elevated blood pressure (BP) measured during the ED visit is controversial. We evaluated the relationship between ED BP and mean BP over the subsequent year. Methods and Results We performed a retrospective cohort study from January 1, 2010 to December 31, 2013 of 8105 adult patients who made 1 visit to an academic medical center ED with ≥2 ED BPs and ≥2 BPs measured in the subsequent year. The primary exposure was lowest ED systolic BP. The primary outcome was mean systolic BP ≥140 mm Hg over the year following the index ED visit. Diastolic BP was examined as a secondary exposure and outcome. Multiple logistic regression was performed adjusting for several covariates, with interaction terms for hypertension diagnosis, ED disposition, pain-related ED chief complaint, and sex. Patients whose lowest ED systolic BP was 140 to 159 mm Hg had an adjusted odds ratio of having a mean SBP ≥140 mm Hg in the subsequent year of 10.9 (95% CI, 7.6-15.6). Patients without diagnosed hypertension and ED BP 140/90 to 159/99 mm Hg were more likely to have elevated BP in the following year. Hospitalization increased the likelihood of persistently elevated systolic BP but not diastolic BP. There was no effect modification by pain-related ED complaint. Conclusions When ED BP is consistently elevated, BP is highly likely to remain elevated in the subsequent year, regardless of pain, and particularly among patients without diagnosed hypertension. Further research is needed to determine the optimal management of elevated ED BP.
高血压患者到急诊科(ED)就诊的人数不断增加,但 ED 就诊时测量的血压升高的重要性仍存在争议。我们评估了 ED 血压与随后一年的平均血压之间的关系。
我们进行了一项回顾性队列研究,纳入了 2010 年 1 月 1 日至 2013 年 12 月 31 日期间在学术医疗中心 ED 就诊的 8105 例至少就诊 2 次、且随后一年中至少测量 2 次血压的成年患者。主要暴露因素为最低 ED 收缩压。主要结局为在 ED 就诊后 1 年内平均收缩压≥140mmHg。我们将舒张压作为次要暴露因素和结局进行研究。使用多元逻辑回归进行分析,调整了多个协变量,包括高血压诊断、ED 处置、与疼痛相关的 ED 主要主诉以及性别。ED 最低收缩压为 140 至 159mmHg 的患者,在随后的 1 年内平均 SBP≥140mmHg 的校正比值比为 10.9(95%CI,7.6-15.6)。未被诊断为高血压且 ED 血压为 140/90 至 159/99mmHg 的患者在接下来的 1 年更有可能出现血压升高。住院增加了持续性收缩压升高的可能性,但不会增加舒张压升高的可能性。与疼痛相关的 ED 主诉不会影响这种相关性。
当 ED 血压持续升高时,无论疼痛情况如何,接下来的 1 年内血压很可能仍处于升高状态,特别是在没有被诊断为高血压的患者中。需要进一步研究来确定 ED 血压升高的最佳管理方法。