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在急诊科,血压升高很常见,但它们重要吗?一项对 30278 名成年人的回顾性队列研究。

Elevated Blood Pressures Are Common in the Emergency Department but Are They Important? A Retrospective Cohort Study of 30,278 Adults.

机构信息

Division of General Internal Medicine, University of Alberta, Edmonton, Alberta, Canada; Alberta SPOR Support Unit Data Platform, University of Alberta, Edmonton, Alberta, Canada.

Alberta SPOR Support Unit Data Platform, University of Alberta, Edmonton, Alberta, Canada.

出版信息

Ann Emerg Med. 2021 Apr;77(4):425-432. doi: 10.1016/j.annemergmed.2020.11.005. Epub 2021 Feb 10.

Abstract

STUDY OBJECTIVE

We determine the frequency of elevated blood pressure (BP) readings in the emergency department (ED), the proportion of patients with prior or subsequent diagnosis of hypertension assigned in other settings, and the association between ED BP levels and cardiovascular outcomes after ED discharge.

METHODS

This was a retrospective cohort study using electronic medical records for all adults treated and released from a large-volume ED in 2016 that were linked to administrative records for all health care encounters in the province for 2 years before and after the index ED visit. The primary outcome measure was a composite of stroke or transient ischemic attack, acute coronary syndrome, new heart failure, or death.

RESULTS

Of 30,278 adults treated and released from the ED, 14,717 (48.6%) had elevated BP readings; 10,732 (72.9%) had no prior diagnosis of hypertension. Of the 3,480 patients with no prior diagnosis of hypertension but an ED BP greater than or equal to 160/100 mm Hg, 907 (26.1%) subsequently received a diagnosis of chronic hypertension or were prescribed antihypertensive therapy in other settings within 2 years. Among patients without a history of hypertension, those with an ED BP greater than or equal to 160/100 mm Hg were more likely to meet the composite outcome (stroke, transient ischemic attack, acute coronary syndrome, heart failure, or death) in the subsequent year (3.3% versus 2.5%) or 2 years (5.9% versus 3.8%) than those with ED BPs 120 to 139/80 to 89 mm Hg; however, after adjusting for age, sex, diabetes, atrial fibrillation, and prior cardiovascular disease, their risk was not elevated (adjusted hazard ratio 0.84; 95% confidence interval 0.71 to 1.004 during 2 years).

CONCLUSION

Elevated BP readings in the ED are common and are often the first time hypertension is detected; however, they were not associated with adverse cardiovascular outcomes within 2 years of the visit.

摘要

研究目的

我们确定了急诊科(ED)中血压升高(BP)读数的频率、在其他环境中诊断为高血压的患者比例,以及 ED BP 水平与 ED 出院后心血管结局之间的关联。

方法

这是一项回顾性队列研究,使用了 2016 年从一家大容量 ED 治疗并出院的所有成年人的电子病历,并与该省在就诊前 2 年和就诊后 2 年内所有医疗保健接触的行政记录相链接。主要结局指标是卒中或短暂性脑缺血发作、急性冠状动脉综合征、新发心力衰竭或死亡的综合指标。

结果

在从 ED 治疗并出院的 30278 名成年人中,有 14717 人(48.6%)的 BP 读数升高;10732 人(72.9%)没有高血压的既往诊断。在 3480 名没有高血压既往诊断但 ED BP 大于或等于 160/100mmHg 的患者中,有 907 人(26.1%)随后在 2 年内被诊断为慢性高血压或在其他环境中被处方了降压治疗。在没有高血压病史的患者中,ED BP 大于或等于 160/100mmHg 的患者在随后的 1 年(3.3%比 2.5%)或 2 年(5.9%比 3.8%)更有可能出现复合结局(卒中、短暂性脑缺血发作、急性冠状动脉综合征、心力衰竭或死亡);然而,在调整年龄、性别、糖尿病、心房颤动和既往心血管疾病后,他们的风险并未升高(调整后的危险比 0.84;95%置信区间 0.71 至 1.004,在 2 年内)。

结论

ED 中 BP 升高很常见,并且通常是首次发现高血压;然而,在就诊后 2 年内,它们与不良心血管结局无关。

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