Sood Anubhuti, Mishra Deepika, Yadav Rahul, Bhatt Krushna, Priya Harsh, Kaur Harpreet
Division of Oral Pathology and Microbiology, Center for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
Division of Oral and Maxillofacial Surgery, Center for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
J Oral Maxillofac Pathol. 2020 Jan-Apr;24(1):52-56. doi: 10.4103/jomfp.JOMFP_273_19. Epub 2020 May 8.
High cost of tools used for the collection of oral cytology sample; deters their use as mass screening tool in the developing countries. Hence, this study aims to assess the diagnostic accuracy of a new, cheaper sample collection tool in the field of oral exfoliative cytology through comparison with histopathology.
Fifty-seven patients out of 394 cases were selected for the study in whom the cytological examination was performed using the wooden end of a sterile cotton swab followed by biopsy. The cytological smear classified in accordance with the Pap classification was compared with the histopathological diagnosis.
The study recruited 11 cases of oral potentially malignant disorders, 33 cases of oral carcinomas, and 13 cases of other lesions. The sensitivity and specificity of the cytology test using the wooden end of a sterile cotton swab was 75.0% and 61.5%, respectively. The Spearman's correlation coefficient was 0.618, with the < 0.01.
Our study proves that the use of wooden end of a sterile cotton swab stick offers a low cost and fairly effective solution which is not only easily available but can be potentially applied as a mass screening tool at primary health-care centers.
用于采集口腔细胞学样本的工具成本高昂，这阻碍了其在发展中国家作为大规模筛查工具的使用。因此，本研究旨在通过与组织病理学进行比较，评估一种新型、更便宜的样本采集工具在口腔脱落细胞学领域的诊断准确性。
从394例病例中选取57例患者进行研究，先用无菌棉签的木质端进行细胞学检查，然后进行活检。将根据巴氏分类法分类的细胞学涂片与组织病理学诊断结果进行比较。
该研究纳入了11例口腔潜在恶性疾病、33例口腔癌和13例其他病变。使用无菌棉签木质端进行细胞学检测的敏感性和特异性分别为75.0%和61.5%。Spearman相关系数为0.618，P<0.01。
我们的研究证明，使用无菌棉签的木质端提供了一种低成本且相当有效的解决方案，它不仅容易获得，而且有可能在初级卫生保健中心用作大规模筛查工具。
