Singh Shruti, Singh Jaya, Chandra Shaleen, Samadi Fahad Mansoor
Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India.
J Oral Maxillofac Pathol. 2020 Jan-Apr;24(1):87-92. doi: 10.4103/jomfp.JOMFP_347_19. Epub 2020 May 8.
Despite our sincere and serious efforts, oral cancer (particularly oral squamous cell carcinoma [OSCC]) is the major cause of morbidity and mortality in the Indian population. Oral precancerous lesions show quite high malignant transformation rate. Epidemiological data of oral epithelial dysplasia (OED) and OSCC could help in early diagnosis and thus may improve the prognosis. The current study aims to retrospectively analyze the epidemiological profile of patients with different grades of OED and OSCCs.
The current study is a retrospective analysis of OED and OSCC reported in 5 years in our institution from 2014 to 2018. Data for the analysis were attained from the case sheets from the patients diagnosed with OED and OSCC.
The mean prevalence of OED and OSCC was 5.71% and 9.85%, respectively. Among the dysplastic lesions, severe dysplasia was more common, while well-differentiated squamous cell carcinoma was more common among the carcinomatous lesions. The peak age prevalence of both the lesions was third to fifth decade. Males were more frequently affected than females, with buccal mucosa being the most common site.
The data attained from this study highlight the need for community-based screening and awareness programs for general population and thus obtain a healthier society.
尽管我们付出了真诚且认真的努力,但口腔癌(尤其是口腔鳞状细胞癌[OSCC])仍是印度人口发病和死亡的主要原因。口腔癌前病变显示出相当高的恶变率。口腔上皮发育异常(OED)和OSCC的流行病学数据有助于早期诊断,从而可能改善预后。本研究旨在回顾性分析不同等级OED和OSCC患者的流行病学特征。
本研究是对2014年至2018年我院5年间报告的OED和OSCC进行的回顾性分析。分析数据来自诊断为OED和OSCC患者的病历表。
OED和OSCC的平均患病率分别为5.71%和9.85%。在发育异常病变中,重度发育异常更为常见,而在癌性病变中,高分化鳞状细胞癌更为常见。两种病变的年龄患病率高峰均在第三至第五个十年。男性比女性更易受影响,颊黏膜是最常见的部位。
本研究获得的数据凸显了针对普通人群开展基于社区的筛查和提高认识项目的必要性,从而实现社会更加健康。