口腔鳞状细胞癌的临床流行病学研究：印度北部一家三级护理中心的研究
Clinico-epidemiological study of oral squamous cell carcinoma: A tertiary care centre study in North India.
作者信息
Singh Mahendra Pratap, Kumar Vijay, Agarwal Akash, Kumar Rajendra, Bhatt M L B, Misra Sanjeev
机构信息
Department of Surgical Oncology, King George's Medical University, Lucknow, UP, India.
Department of Surgical Oncology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Vibhuti Khand, Gomtinagar, Lucknow, UP, India.
出版信息
J Oral Biol Craniofac Res. 2016 Jan-Apr;6(1):31-4. doi: 10.1016/j.jobcr.2015.11.002. Epub 2015 Dec 4.
Abstract
INTRODUCTION
Oral squamous cell carcinoma (OSCC) ranks 12th most common cancer in the world.
OBJECTIVE
The aim of this study was to retrospectively evaluate the OSCC.
METHODS
A retrospective study of 611 OSCC patients from January 2010 to December 2013 was carried out in Department of Surgical Oncology, King George's Medical University, Lucknow, India. Details of patient's sex, age, tobacco habit and site of cancer were noted. Data were analyzed by Student's t test and chi-squire (χ (2)) test.
RESULTS
The prevalence of OSCC was significantly (p < 0.001) higher in males (75.9%) than females (24.1%). The mean age of female patients was higher than males (p < 0.001). In both the genders, the buccal mucosa and gingivobuccal sulcus were found to be the most affected sites. Moreover, the smokeless form of tobacco was found to be significantly associated with OSCC, especially in females.
CONCLUSION
The study concluded that OSCC is more common in men as compared to women, probably due to habit of tobacco consumption. Smokeless tobacco use is an important risk factor, especially in females.
摘要
引言
口腔鳞状细胞癌（OSCC）是全球第12大常见癌症。
目的
本研究旨在对口腔鳞状细胞癌进行回顾性评估。
方法
在印度勒克瑙市乔治国王医科大学外科肿瘤学系，对2010年1月至2013年12月期间的611例口腔鳞状细胞癌患者进行了一项回顾性研究。记录了患者的性别、年龄、吸烟习惯和癌症发生部位的详细信息。数据采用学生t检验和卡方（χ(2)）检验进行分析。
结果
口腔鳞状细胞癌的患病率在男性（75.9%）中显著（p < 0.001）高于女性（24.1%）。女性患者的平均年龄高于男性（p < 0.001）。在男女两性中，颊黏膜和龈颊沟是受影响最严重的部位。此外，发现无烟烟草形式与口腔鳞状细胞癌显著相关，尤其是在女性中。
结论
该研究得出结论，与女性相比，口腔鳞状细胞癌在男性中更为常见，这可能是由于烟草消费习惯所致。无烟烟草的使用是一个重要的危险因素，尤其是在女性中。
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