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胃黏膜相关淋巴组织淋巴瘤患者的二次癌症

Second Cancers in a Patient with Gastric MALT Lymphoma.

作者信息

Navsaria Lucy, Badillo Alfonso, Wang Michael

机构信息

Department of Lymphoma and Myeloma, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

出版信息

Case Rep Med. 2020 May 13;2020:1213596. doi: 10.1155/2020/1213596. eCollection 2020.

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma is an extranodal low-grade B-cell lymphoma, which is thought to arise from a background of chronic immune stimulation, bacterial, viral, or autoimmune stimuli. Treatment advances have increased the number of MALT lymphoma survivors, but there is still debate as to whether these patients are at a higher risk of developing second cancers. This is a case of a long-surviving (>20 years) patient with multiple diagnosed malignancies following MALT lymphoma. We describe how modern oncological treatment plans can provide patients with prolonged survival and increased quality of life despite increasing age and multiple malignancies.

摘要

黏膜相关淋巴组织(MALT)淋巴瘤是一种结外低度B细胞淋巴瘤,被认为起源于慢性免疫刺激、细菌、病毒或自身免疫刺激的背景。治疗进展增加了MALT淋巴瘤幸存者的数量,但对于这些患者是否有更高的患第二癌症风险仍存在争议。这是一例MALT淋巴瘤后长期存活(>20年)且诊断出多种恶性肿瘤的患者。我们描述了尽管患者年龄增加且患有多种恶性肿瘤,但现代肿瘤治疗方案如何能为患者提供延长的生存期和更高的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e37/7244950/33b94f28f369/CRIM2020-1213596.001.jpg

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