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社区获得性肺炎对慢性阻塞性肺疾病患者急性加重期住院并发症及早期再入院的影响

The Impact of Community-acquired Pneumonia on Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients as Regards In-hospital Complications and Early Readmission.

作者信息

Ruby Dina

机构信息

Chest Department, Ain Shams University, Cairo, Egypt.

出版信息

Open Respir Med J. 2020 Apr 9;14:10-15. doi: 10.2174/1874306402014010010. eCollection 2020.

Abstract

BACKGROUND AND OBJECTIVE

Pneumonia is a major reason for hospitalization for Acute Exacerbation of Chronic Obstructive Pulmonary Disease patients (AECOPD). There is limited data available on the outcomes of AECOPD patients with or without pneumonia. Therefore, the study investigates the prognosis of AECOPD patients with or without Community-acquired Pneumonia (CAP), concerning the Length of Hospital Stay (LOS), in-hospital complications and early readmission.

METHODS

This study was carried out on 100 male COPD patients without CAP, 90 patients with CAP who were admitted to the chest department of Ain Shams University hospital over a 1-year period. Data collection about LOS, in-hospital complications, was recorded and they were followed for 30 days to detect acute readmission.

RESULTS

The mean age was 64± 8 years old in COPD patients without CAP to 62± 12year old in patients with CAP, LOS in COPD patients with CAP was 11.30 ± 3.23 days to 7.57 ± 2.24 in patients without CAP, COPD patients with CAP had a higher rate of complications in comparison to those without CAP as 45.6%, 13% were admitted to Intensive Care Unit (ICU) respectively, 15.6%, 3% were mechanically ventilated respectively. LOS and C- Reactive Protein (CRP) were significant causes for readmission in COPD patients with and without CAP.

CONCLUSION

COPD patients with CAP had longer LOS and more short term complications as ICU admission, mechanical ventilation and higher readmission rate in comparison to COPD patients without CAP.

摘要

背景与目的

肺炎是慢性阻塞性肺疾病急性加重期(AECOPD)患者住院治疗的主要原因。关于合并或未合并肺炎的AECOPD患者的预后数据有限。因此,本研究调查了合并或未合并社区获得性肺炎(CAP)的AECOPD患者的预后情况,涉及住院时间(LOS)、院内并发症和早期再入院情况。

方法

本研究对100例未合并CAP的男性COPD患者以及1年内入住艾因夏姆斯大学医院胸科的90例合并CAP的患者进行。记录了关于LOS、院内并发症的数据,并对他们进行了30天的随访以检测急性再入院情况。

结果

未合并CAP的COPD患者的平均年龄为64±8岁,合并CAP的患者为62±12岁;合并CAP的COPD患者的LOS为11.30±3.23天,未合并CAP的患者为7.57±2.24天;与未合并CAP的患者相比,合并CAP的COPD患者并发症发生率更高,分别为45.6%、13%入住重症监护病房(ICU),分别为15.6%、3%接受机械通气。LOS和C反应蛋白(CRP)是合并和未合并CAP的COPD患者再入院的重要原因。

结论

与未合并CAP的COPD患者相比,合并CAP的COPD患者LOS更长,短期并发症更多,如入住ICU、机械通气,再入院率更高。

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