Sun Yajing, Zheng Jie, Jiang Zhongmin, Zhang Lidong, Ding Shanshan, Liu Xiaozhi
Department of Pathology, Tianjin Fifth Central Hospital 41 Zhejiang Road, Tanggu District, Tianjin, China.
Department of Pathology, Chinese People's Liberation Army Rocket General Hospital 16 Xinjiekouwai Street, Xicheng District, Beijing, China.
Int J Clin Exp Pathol. 2020 May 1;13(5):896-900. eCollection 2020.
Placental mesenchymal dysplasia (PMD) is a rare disorder of unknown etiology, which is often misdiagnosed as partial hydatidiform mole because of their similarity in ultrasonographic, gross, and histologic presentations. However, the treatment and prognosis of these two conditions are different. Patients with PMD often have intrauterine growth restriction, intrauterine fetal death, and Beckwith-Wiedemann syndrome, but there may also be a normal fetus. PMD with a normal female infant is extremely rare, and only a few cases have been reported. We report a case of PMD in a normal female infant and its follow-up results.
胎盘间充质发育异常(PMD)是一种病因不明的罕见疾病,由于其在超声、大体和组织学表现上与部分性葡萄胎相似,常被误诊为部分性葡萄胎。然而,这两种疾病的治疗方法和预后不同。PMD患者常出现宫内生长受限、宫内胎儿死亡和贝克威思-维德曼综合征,但也可能有正常胎儿。PMD合并正常女婴极为罕见,仅有少数病例报道。我们报告一例正常女婴的PMD病例及其随访结果。